Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus

Overview

Journal Nutrients

Date 2021 Jan 28

PMID 33503923

Citations 6

Authors

Kalliopi Gkouskou

Evgenia Lazou

Efstathios Skoufas

Aristides G Eliopoulos

Affiliations

Soon will be listed here.

Abstract

The current consensus for the prevention and management of type 2 diabetes mellitus (T2DM) is that high-quality diets and adherence to a healthy lifestyle provide significant health benefits. Remarkably, however, there is little agreement on the proportions of macronutrients in the diet that should be recommended to people suffering from pre-diabetes or T2DM. We herein discuss emerging evidence that underscores the importance of gene-diet interactions in the improvement of glycemic biomarkers in T2DM. We propose that we can achieve better glycemic control in T2DM patients by coupling Mediterranean diets to genetic information as a predictor for optimal diet macronutrient composition in a personalized manner. We provide evidence to support this concept by presenting a case study of a T2DM patient who achieved rapid glycemic control when adhered to a personalized, genetically-guided Mediterranean Diet.

Citing Articles

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Genotype-based precision nutrition strategies for the prediction and clinical management of type 2 diabetes mellitus.

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