Combination of High-frequency Ultrasound and Virtual Touch Tissue Imaging and Quantification Improve the Diagnostic Efficiency for Mild Carpal Tunnel Syndrome

Overview

Journal BMC Musculoskelet Disord

Publisher Biomed Central

Specialties Orthopedics
Physiology

Date 2021 Jan 27

PMID 33499842

Citations 3

Authors

Zhen-Han Lai

Shu-Ping Yang

Hao-Lin Shen

Yi Luo

Xiao-Han Cai

Wen-Ting Jiang

Li-Ping Liao

Kun-Bin Wu

Guo-Rong Lv

Affiliations

Soon will be listed here.

Abstract

Background: Carpal tunnel syndrome (CTS) is the most common entrapment symptom in the peripheral nerves. High-frequency ultrasound (HFUS) is widely used in the diagnosis of CTS. Virtual Touch Tissue Imaging and Quantification (VTIQ), which provides more information about the hardness of organization, is used to diagnose CTS. However, the data of diagnostic value of them in various degrees of CTS are limited. Whether the combination of HFUS and VTIQ can improve the diagnostic efficiency also remains unknown. The study aimed to explore the diagnostic value of HFUS and VTIQ in various degrees of CTS and whether combination of HFUS and VTIQ could improve the diagnostic efficiency of CTS.

Methods: A collection and analysis of 133 CTS patients and 35 volunteers from January 2016 to January 2019 were performed. We compared the clinical characteristics, cross-sectional area (CSA) value and shear wave velocity SWV value of CTS group with volunteer group.

Results: The CSA value and SWV value of CTS cohort were significantly higher than volunteer group (10.79 ± 2.88 vs. 8.06 ± 1.39, p < 0.001, 4.36 ± 0.95 vs. 3.38 ± 1.09, p < 0.001, respectively). The area under the curve (AUC) of receiver operating characteristic (ROC) curve of CSA value and SWV value were 0.794 and 0.757, respectively. Hierarchical analysis of CSA value and SWV value showed that the AUC in the moderate and severe CTS group were higher than in mild CTS group. Furthermore, the CSA value combined with SWV value used to diagnose mild CTS was 0.758, which was higher than that of single CSA value or single SWV value.

Conclusions: Both HFUS and VTIQ technology were feasible to evaluate CTS. HFUS was suitable for use in diagnosis of moderate and severe CTS. For mild CTS, combination of HFUS and VTIQ was relevant to improve the diagnostic efficiency of CTS.

Citing Articles

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The Impact of Reference Standard on Diagnostic Testing Characteristics for Carpal Tunnel Syndrome: A Systematic Review.

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