Odor Response Adaptation in Drosophila-a Continuous Individualization Process

Overview

Journal Cell Tissue Res

Specialties Anatomy & Histology
Cell Biology

Date 2021 Jan 25

PMID 33492517

Citations 3

Authors

Shadi Jafari

Mattias Alenius

Affiliations

Soon will be listed here.

Abstract

Olfactory perception is very individualized in humans and also in Drosophila. The process that individualize olfaction is adaptation that across multiple time scales and mechanisms shape perception and olfactory-guided behaviors. Olfactory adaptation occurs both in the central nervous system and in the periphery. Central adaptation occurs at the level of the circuits that process olfactory inputs from the periphery where it can integrate inputs from other senses, metabolic states, and stress. We will here focus on the periphery and how the fast, slow, and persistent (lifelong) adaptation mechanisms in the olfactory sensory neurons individualize the Drosophila olfactory system.

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References

Hong E, Wilson R . Simultaneous encoding of odors by channels with diverse sensitivity to inhibition. Neuron. 2015; 85(3):573-89. PMC: 5495107. DOI: 10.1016/j.neuron.2014.12.040. View

von der Weid B, Rossier D, Lindup M, Tuberosa J, Widmer A, Col J . Large-scale transcriptional profiling of chemosensory neurons identifies receptor-ligand pairs in vivo. Nat Neurosci. 2015; 18(10):1455-63. DOI: 10.1038/nn.4100. View

Wilson R, Laurent G . Role of GABAergic inhibition in shaping odor-evoked spatiotemporal patterns in the Drosophila antennal lobe. J Neurosci. 2005; 25(40):9069-79. PMC: 6725763. DOI: 10.1523/JNEUROSCI.2070-05.2005. View

Bahk S, Jones W . Insect odorant receptor trafficking requires calmodulin. BMC Biol. 2016; 14(1):83. PMC: 5043534. DOI: 10.1186/s12915-016-0306-x. View

Golovin R, Vest J, Vita D, Broadie K . Activity-Dependent Remodeling of Olfactory Sensory Neuron Brain Innervation during an Early-Life Critical Period. J Neurosci. 2019; 39(16):2995-3012. PMC: 6468095. DOI: 10.1523/JNEUROSCI.2223-18.2019. View

Iyengar A, Chakraborty T, Goswami S, Wu C, Siddiqi O . Post-eclosion odor experience modifies olfactory receptor neuron coding in Drosophila. Proc Natl Acad Sci U S A. 2010; 107(21):9855-60. PMC: 2906832. DOI: 10.1073/pnas.1003856107. View

Martelli C, Fiala A . Slow presynaptic mechanisms that mediate adaptation in the olfactory pathway of . Elife. 2019; 8. PMC: 6581506. DOI: 10.7554/eLife.43735. View

Abdus-Saboor I, Al Nufal M, Agha M, Ruinart de Brimont M, Fleischmann A, Shykind B . An Expression Refinement Process Ensures Singular Odorant Receptor Gene Choice. Curr Biol. 2016; 26(8):1083-90. DOI: 10.1016/j.cub.2016.02.039. View

Jafari S, Henriksson J, Yan H, Alenius M . Stress and odorant receptor feedback during a critical period after hatching regulates olfactory sensory neuron differentiation in Drosophila. PLoS Biol. 2021; 19(4):e3001101. PMC: 8043390. DOI: 10.1371/journal.pbio.3001101. View

10.

Hensch T . Critical period regulation. Annu Rev Neurosci. 2004; 27:549-79. DOI: 10.1146/annurev.neuro.27.070203.144327. View

11.

Deng Y, Zhang W, Farhat K, Oberland S, Gisselmann G, Neuhaus E . The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila. PLoS One. 2011; 6(4):e18605. PMC: 3072409. DOI: 10.1371/journal.pone.0018605. View

12.

Winther A, Ignell R . Local peptidergic signaling in the antennal lobe shapes olfactory behavior. Fly (Austin). 2010; 4(2):167-71. DOI: 10.4161/fly.4.2.11467. View

13.

Carlsson M, Diesner M, Schachtner J, Nassel D . Multiple neuropeptides in the Drosophila antennal lobe suggest complex modulatory circuits. J Comp Neurol. 2010; 518(16):3359-80. DOI: 10.1002/cne.22405. View

14.

Root C, Ko K, Jafari A, Wang J . Presynaptic facilitation by neuropeptide signaling mediates odor-driven food search. Cell. 2011; 145(1):133-44. PMC: 3073827. DOI: 10.1016/j.cell.2011.02.008. View

15.

Sim C, Perry S, Tharadra S, Lipsick J, Ray A . Epigenetic regulation of olfactory receptor gene expression by the Myb-MuvB/dREAM complex. Genes Dev. 2012; 26(22):2483-98. PMC: 3505819. DOI: 10.1101/gad.201665.112. View

16.

Vosshall L, Amrein H, Morozov P, Rzhetsky A, Axel R . A spatial map of olfactory receptor expression in the Drosophila antenna. Cell. 1999; 96(5):725-36. DOI: 10.1016/s0092-8674(00)80582-6. View

17.

Das S, Sadanandappa M, Dervan A, Larkin A, Lee J, Sudhakaran I . Plasticity of local GABAergic interneurons drives olfactory habituation. Proc Natl Acad Sci U S A. 2011; 108(36):E646-54. PMC: 3169145. DOI: 10.1073/pnas.1106411108. View

18.

Jones W, Nguyen T, Kloss B, Lee K, Vosshall L . Functional conservation of an insect odorant receptor gene across 250 million years of evolution. Curr Biol. 2005; 15(4):R119-21. DOI: 10.1016/j.cub.2005.02.007. View

19.

Guo H, Kunwar K, Smith D . Odorant Receptor Sensitivity Modulation in . J Neurosci. 2017; 37(39):9465-9473. PMC: 5618264. DOI: 10.1523/JNEUROSCI.1573-17.2017. View

20.

Olsen S, Wilson R . Lateral presynaptic inhibition mediates gain control in an olfactory circuit. Nature. 2008; 452(7190):956-60. PMC: 2824883. DOI: 10.1038/nature06864. View