Comparison of Mental Health, Quality of Sleep and Life Among Patients with Different Stages of Chronic Kidney Disease and Undergoing Different Renal Replacement Therapies

Overview

Journal Hippokratia

Specialty General Medicine

Date 2021 Jan 25

PMID 33488052

Citations 2

Authors

O Kucuk

K Kaynar

F C Arslan

S Ulusoy

H K Gul

A Celik

G Can

Affiliations

Soon will be listed here.

Abstract

Background: The present study aimed to investigate and compare mental health, health-related quality of life, and sleep levels of patients with various stages of chronic kidney disease (CKD) and undergoing different renal replacement therapies and analyze the factors affecting these parameters.

Methods: Overall, 140 patients with a mean age of 43 ± 14 years were recruited into this study. Study groups [controls and patients with CKD undergoing predialysis, hemodialysis (HD), peritoneal dialysis, kidney transplantation (KT)] were evaluated using Short Form Health Survey-36 (SF-36), Kidney Disease Quality of Life-36 (KDQoL-36), Pittsburgh Sleep Quality Index (PSQI), and General Health Questionnaire-12 (GHQ-12).

Results: The KT group had the highest scores in physical and mental components of the subscales of SF-36 and KDQoL-36 but the lowest scores in PSQI and GHQ-12, indicating the best results in terms of mental health and quality of life, and sleep. Serum albumin and hemoglobin levels were positively correlated with several subscales of quality of life. Significant negative correlations were observed among PSQI, GHQ-12, and subscale scores of SF-36 and KDQoL-36. The HD group showed significantly lower scores in the subscales of symptoms and burden of kidney disease of KDQoL-36.

Conclusion: KDQoL was worse in the HD group and better in the KT group than in other groups. Serum albumin and hemoglobin levels, and Kt/V (dialyzer clearance of urea multiplied by dialysis time and normalized for urea distribution volume ) values of patients with CKD exerted a linear and significant effect on the quality of life, which showed a significant positive correlation with the quality of sleep and mental health. In contrast, serum calcium x phosphorus levels showed an inverse correlation with the subscale scores of KDQoL. HIPPOKRATIA 2020, 24(2): 51-58.

Citing Articles

The association of sleep duration with the risk of chronic kidney disease: a systematic review and meta-analysis.

Koh J, Yeo B, Tan T, See M, Ng A, Loh S Clin Kidney J. 2024; 17(8):sfae177.

PMID: 39114497 PMC: 11304598. DOI: 10.1093/ckj/sfae177.

Self-reported poor quality of sleep in solid organ transplant: A systematic review.

Cordoza M, Koons B, Perlis M, Anderson B, Diamond J, Riegel B Transplant Rev (Orlando). 2021; 35(4):100650.

PMID: 34534733 PMC: 8526478. DOI: 10.1016/j.trre.2021.100650.

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