Economical and Easily Detectable Markers of Digestive Tumors: Platelet Parameters

Overview

Journal Biomark Med

Specialties Biochemistry
General Medicine

Date 2021 Jan 21

PMID 33474972

Citations 3

Authors

Yingying Chen

Wei Yang

Lifang Ye

Suzhen Lin

Kuangyi Shu

Xiao Yang

Xinyi Ai

Yating Yao

Minghua Jiang

Affiliations

Soon will be listed here.

Abstract

This study aimed to evaluate the clinical values of platelet parameters in patients with digestive tumors. A total of 974 people were classified into three groups: malignant group, patients with digestive malignant tumors; benign group, patients with benign tumors; and normal group: healthy individuals. Compared with the benign and normal groups, the malignant group showed significantly increased platelet count (PLT) and plateletcrit (PCT) and significantly reduced mean platelet volume (MPV) and platelet-large cell rate (P-LCR, p < 0.001). Elevated PLT and PCT and reduced MPV and P-LCR indicated poor overall survival in patients with digestive tumors. PLT, PCT, MPV and P-LCR were proven to be predictive biomarkers for patients with digestive malignant tumors. Elevated PLT and PCT or decreased MPV and P-LCR indicated poor overall survival.

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