Uncommon Cause of Cardiac Tamponade in a Young Man

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2021 Jan 21

PMID 33472808

Authors

Ananthu Narayan

Vineeta Ojha

Sudheer Arava

Animesh Ray

Affiliations

Soon will be listed here.

Abstract

We report a rare case of cardiac angiosarcoma in a young boy who presented with cardiac tamponade. His initial symptoms were non-specific. He was initially being managed in the line of fungal infection, with a possibility of malignancy. Cardiac imaging was also not conclusive and he worsened on antibiotics and antifungals and succumbed to the illness. After his death tissue biopsy from heart and lung was done and histopathological examination revealed the diagnosis of metastatic angiosarcoma. The case highlights the importance of considering the diagnosis of cardiac angiosarcoma in the patients presenting with haemorrhagic pericardial effusion and non-specific symptoms.

References

Patel S, Peterson A, Bartczak A, Lee S, Chojnowski S, Gajewski P . Primary cardiac angiosarcoma - a review. Med Sci Monit. 2014; 20:103-9. PMC: 3907509. DOI: 10.12659/MSM.889875. View

Uberfuhr P, Meiser B, Fuchs A, Schulze C, Reichenspurner H, Falk M . Heart transplantation: an approach to treating primary cardiac sarcoma?. J Heart Lung Transplant. 2002; 21(10):1135-9. DOI: 10.1016/s1053-2498(02)00409-6. View

Kim D, Hong J, Kim S, Yoo K, Seo J, Rhee K . Primary cardiac angiosarcoma presenting with cardiac tamponade. Korean Circ J. 2010; 40(2):86-9. PMC: 2827808. DOI: 10.4070/kcj.2010.40.2.86. View

Centofanti P, Di Rosa E, Deorsola L, Dato G, Patane F, La Torre M . Primary cardiac tumors: early and late results of surgical treatment in 91 patients. Ann Thorac Surg. 1999; 68(4):1236-41. DOI: 10.1016/s0003-4975(99)00700-6. View

Casha A, Davidson L, Roberts P, Nair R . Familial angiosarcoma of the heart. J Thorac Cardiovasc Surg. 2002; 124(2):392-4. DOI: 10.1067/mtc.2002.122314. View

Hamidi M, Moody J, Weigel T, Kozak K . Primary cardiac sarcoma. Ann Thorac Surg. 2010; 90(1):176-81. PMC: 4201046. DOI: 10.1016/j.athoracsur.2010.03.065. View

Oh S, Yeom S, Kim K . Clinical implication of surgical resection for the rare cardiac tumors involving heart and great vessels. J Korean Med Sci. 2013; 28(5):717-24. PMC: 3653084. DOI: 10.3346/jkms.2013.28.5.717. View

Ge Y, Ro J, Kim D, Kim C, Reardon M, Blackmon S . Clinicopathologic and immunohistochemical characteristics of adult primary cardiac angiosarcomas: analysis of 10 cases. Ann Diagn Pathol. 2011; 15(4):262-7. DOI: 10.1016/j.anndiagpath.2011.02.007. View

Riles E, Gupta S, Wang D, Tobin K . Primary cardiac angiosarcoma: A diagnostic challenge in a young man with recurrent pericardial effusions. Exp Clin Cardiol. 2012; 17(1):39-42. PMC: 3383367. View

10.

Brandt R, Arnold R, Bohle R, Dill T, Hamm C . Cardiac angiosarcoma: case report and review of the literature. Z Kardiol. 2005; 94(12):824-8. DOI: 10.1007/s00392-005-0296-0. View

11.

Mumoli N, Cei M, Gambaccini L, Sabatini S, Vitale J . Hodgkin disease complicated by recurrent cardiac tamponade. QJM. 2013; 106(9):859-60. DOI: 10.1093/qjmed/hct084. View

12.

Antonuzzo L, Rotella V, Mazzoni F, Doni L, Bianchini D, Garbini F . Primary cardiac angiosarcoma: a fatal disease. Case Rep Med. 2009; 2009:591512. PMC: 2731464. DOI: 10.1155/2009/591512. View

13.

Rettmar K, Stierle U, Sheikhzadeh A, DIEDERICH K . Primary angiosarcoma of the heart. Report of a case and review of the literature. Jpn Heart J. 1993; 34(5):667-83. DOI: 10.1536/ihj.34.667. View