High Risk Thyroid Nodule Discrimination and Management by Modified TI-RADS

Overview

Journal Cancer Manag Res

Publisher Dove Medical Press

Specialty Oncology

Date 2021 Jan 20

PMID 33469366

Citations 1

Authors

MengHui Li

Lijuan Wei

Fangxuan Li

Yanyan Kan

Xiaofeng Liang

Huan Zhang

Juntian Liu

Affiliations

Soon will be listed here.

Abstract

Objective: Thyroid cancer is the most common primary malignant disorder of the thyroid. We aimed to illustrate the modified TI-RADS report system for differentiating malignant thyroid nodules from benign ones, and especially its role in the management of high risk nodules.

Methods: In this retrospective study, 5,162 healthy individuals who underwent thyroid ultrasound according to modified TI-RADS from January 2014 to December 2014 were enrolled and followed up during the whole 5 years, and the medical data were investigated and reviewed.

Results: The total detection rate of thyroid nodules was 39.40%. The total detection rate of thyroid cancer was 0.66%. Most thyroid cancers were single-shot, located at unilateral, at early clinical stages, without lymph node metastases, and with low recurrence risk. All patients had thyroid papillary carcinoma, except one thyroid medullary carcinoma. Based on modified TI-RADS classification, at the end of 5 years follow-up, more changes of thyroid nodules grade status were observed in grades 4a and above. The higher the grade status, the more malignant advances were occurred. The modified TI-RADS report system played an instructional role in adding medical treatment choice and decision for clinicians.

Conclusion: The modified TI-RADS report system plays an important role in thyroid benign and malignant nodule identification and management.

Citing Articles

Multi-Omics and Management of Follicular Carcinoma of the Thyroid.

Luvhengo T, Bombil I, Mokhtari A, Moeng M, Demetriou D, Sanders C Biomedicines. 2023; 11(4).

PMID: 37189835 PMC: 10135557. DOI: 10.3390/biomedicines11041217.

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