Measuring Eye Deformation Between Planning and Proton Beam Therapy Position Using Magnetic Resonance Imaging

Overview

Journal Phys Imaging Radiat Oncol

Specialty Oncology

Date 2021 Jan 18

PMID 33458341

Citations 5

Authors

Myriam G Jaarsma-Coes

Marina Marinkovic

Eleftheria Astreinidou

Megan S Schuurmans

Femke P Peters

Gregorius P M Luyten

Coen R N Rasch

Jan-Willem M Beenakker

Affiliations

Soon will be listed here.

Abstract

Proton beam therapy (PBT) for uveal melanoma (UM) is performed in sitting position, while the acquisition of the Magnetic resonance (MR)-images for treatment planning is performed in supine position. We assessed the effect of this difference in position on the eye- and tumour- shape. Seven subjects and six UM-patients were scanned in supine and a seating mimicking position. The distances between the tumour/sclera in both positions were calculated. The median distance between both positions was 0.1 mm. Change in gravity direction produced no substantial changes in sclera and tumour shape, indicating that supinely acquired MR-images can be used to plan ocular-PBT.

Citing Articles

Magnetic Resonance Imaging in the Clinical Care for Uveal Melanoma Patients-A Systematic Review from an Ophthalmic Perspective.

Jaarsma-Coes M, Klaassen L, Marinkovic M, Luyten G, Vu T, Ferreira T Cancers (Basel). 2023; 15(11).

PMID: 37296958 PMC: 10252038. DOI: 10.3390/cancers15112995.

Inter-Observer Variability in MR-Based Target Volume Delineation of Uveal Melanoma.

Jaarsma-Coes M, Klaassen L, Verbist B, Vu T, Klaver Y, Rodrigues M Adv Radiat Oncol. 2023; 8(3):101149.

PMID: 36691449 PMC: 9860418. DOI: 10.1016/j.adro.2022.101149.

Clinical and imaging clues to the diagnosis and follow-up of ptosis and ophthalmoparesis.

Keene K, Kan H, van der Meeren S, Verbist B, Tannemaat M, Beenakker J J Cachexia Sarcopenia Muscle. 2022; 13(6):2820-2834.

PMID: 36172973 PMC: 9745561. DOI: 10.1002/jcsm.13089.

Histopathologic and MR Imaging Appearance of Spontaneous and Radiation-Induced Necrosis in Uveal Melanomas: Initial Results.

Foti P, Ini C, Broggi G, Farina R, Palmucci S, Spatola C Cancers (Basel). 2022; 14(1).

PMID: 35008378 PMC: 8750257. DOI: 10.3390/cancers14010215.

Characterization of the HollandPTC proton therapy beamline dedicated to uveal melanoma treatment and an interinstitutional comparison.

Fleury E, Trnkova P, Spruijt K, Herault J, Lebbink F, Heufelder J Med Phys. 2021; 48(8):4506-4522.

PMID: 34091930 PMC: 8457201. DOI: 10.1002/mp.15024.

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