Giant Cell Tumor of the Sacrum

Overview

Journal Proc (Bayl Univ Med Cent)

Specialty General Medicine

Date 2021 Jan 18

PMID 33456178

Citations 1

Authors

James Rizkalla

Brendan Holderread

Jonathan Liu

Al Mollabashy

Ishaq Y Syed

Affiliations

Soon will be listed here.

Abstract

Giant cell tumor of the sacrum is a rare primary tumor in a challenging anatomical location without clear consensus on treatment. We present a case of giant cell tumor of the sacrum and subsequent treatment with preoperative embolization, L5 to S4 laminectomy, partial sacrectomy, intraoperative thermal ablation, and L4 to pelvis stabilization and fusion.

Citing Articles

In situ cryoablation of sacral Giant Cell Tumor using three-dimensional (3D) model: A case report.

Elias A, Benady A, Golden E, Segal O, Dadia S J Orthop. 2022; 30:46-50.

PMID: 35241887 PMC: 8857548. DOI: 10.1016/j.jor.2022.02.007.

References

Martin C, McCarthy E . Giant cell tumor of the sacrum and spine: series of 23 cases and a review of the literature. Iowa Orthop J. 2010; 30:69-75. PMC: 2958273. View

Leggon R, Zlotecki R, Reith J, Scarborough M . Giant cell tumor of the pelvis and sacrum: 17 cases and analysis of the literature. Clin Orthop Relat Res. 2004; (423):196-207. DOI: 10.1097/01.blo.0000128643.38390.07. View

Thangaraj R, Grimer R, Carter S, Stirling A, Spilsbury J, Spooner D . Giant cell tumour of the sacrum: a suggested algorithm for treatment. Eur Spine J. 2010; 19(7):1189-94. PMC: 2900020. DOI: 10.1007/s00586-009-1270-8. View

Bydon M, de la Garza-Ramos R, Bettegowda C, Suk I, Wolinsky J, Ziya L Gokaslan . En Bloc Resection of a Giant Cell Tumor in the Sacrum via a Posterior-Only Approach Without Nerve Root Sacrifice: Technical Case Report. Neurosurgery. 2015; 11 Suppl 3:E472-8. PMC: 4856007. DOI: 10.1227/NEU.0000000000000836. View

Poll A, Nimigean V, Virlan M, Sirbu V, Costache M, Ivascu R . A rare tumor in a rare location: giant cell tumor of the sacrum and ilium - case report and current perspectives. Rom J Morphol Embryol. 2020; 60(3):985-992. View

Boriani S . resection in the spine: a procedure of surgical oncology. J Spine Surg. 2018; 4(3):668-676. PMC: 6261759. DOI: 10.21037/jss.2018.09.02. View

Zheng K, Yu X, Hu Y, Wang Z, Wu S, Ye Z . Surgical treatment for pelvic giant cell tumor: a multi-center study. World J Surg Oncol. 2016; 14:104. PMC: 4820864. DOI: 10.1186/s12957-016-0862-0. View

Tian X, Liu K, Hou Y, Cheng J, Zhang J . The evolution of proton beam therapy: Current and future status. Mol Clin Oncol. 2018; 8(1):15-21. PMC: 5772792. DOI: 10.3892/mco.2017.1499. View

Mohaidat Z, Al-Jamal H, Bany-Khalaf A, Radaideh A, Audat Z . Giant cell tumor of bone: Unusual features of a rare tumor. Rare Tumors. 2019; 11:2036361319878894. PMC: 6764048. DOI: 10.1177/2036361319878894. View

10.

Yang Y, Li Y, Liu W, Xu H, Niu X . A nonrandomized controlled study of sacral giant cell tumors with preoperative treatment of denosumab. Medicine (Baltimore). 2018; 97(46):e13139. PMC: 6257612. DOI: 10.1097/MD.0000000000013139. View

11.

He S, Xu W, Sun Z, Liu W, Liu Y, Wei H . Selective Arterial Embolization for the Treatment of Sacral and Pelvic Giant Cell Tumor: A Systematic Review. Orthop Surg. 2017; 9(2):139-144. PMC: 6584703. DOI: 10.1111/os.12336. View

12.

Shirato H, Le Q, Kobashi K, Prayongrat A, Takao S, Shimizu S . Selection of external beam radiotherapy approaches for precise and accurate cancer treatment. J Radiat Res. 2018; 59(suppl_1):i2-i10. PMC: 5868193. DOI: 10.1093/jrr/rrx092. View

13.

Takeda N, Kobayashi T, Tandai S, Matsuno T, Shirado O, Watanabe T . Treatment of giant cell tumors in the sacrum and spine with curettage and argon beam coagulator. J Orthop Sci. 2009; 14(2):210-4. DOI: 10.1007/s00776-008-1299-2. View