Quantitative Assessment of Bladder Wall Vascularity Index in Children with Acute Cystitis Using Superb Microvascular Imaging

Overview

Journal J Ultrasound

Publisher Springer

Specialty Radiology

Date 2021 Jan 16

PMID 33453056

Citations 4

Authors

Fatih Ates

Mehmet Sedat Durmaz

Alaaddin Yorulmaz

Halil Ibrahim Sara

Affiliations

Soon will be listed here.

Abstract

Purpose: The purpose of this study was to investigate the effectiveness of the vascularization index (VI) obtained using color superb microvascular imaging (cSMI) technique in assessment of the anterior urinary bladder wall in pediatric patients with acute cystitis (AC).

Methods: The anterior bladder wall of 157 patients (age range 13-84 months, mean 43.62 ± 17.79 months) whose clinical and laboratory findings were proven of AC and 150 healthy asymptomatic participants (age range 13-84 months, mean 43.88 ± 18.11 months) with normal laboratory values were examined using cSMI. VI measurements were performed by manually drawing the contours of the anterior bladder wall using the free region of interest with 2-dimensional cSMI VI (2DcSMIVI) mode. The quantitative 2DcSMIVI values of the symptomatic group and the asymptomatic group were compared. The correlation between the 2DcSMIVI values and the anterior bladder wall thickness (BWT) were analyzed.

Results: The mean 2DcSMIVI values of the BWT were significantly higher in symptomatic group when compared to the asymptomatic group (p<0.001). AC can be diagnosed with a 93% sensitivity, 92% specificity when 3.25% 2DcSMIVI designated as the cutoff value. There was a significant positive correlation between 2DcSMIVI values and BWT (p<0.001).

Conclusion: Two-dimensional cSMI VI can be used effectively in children as an imaging method in the diagnosis of AC.

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References

Durmaz M, Sivri M . Comparison of superb micro-vascular imaging (SMI) and conventional Doppler imaging techniques for evaluating testicular blood flow. J Med Ultrason (2001). 2017; 45(3):443-452. DOI: 10.1007/s10396-017-0847-9. View

Tosif S, Baker A, Oakley E, Donath S, Babl F . Contamination rates of different urine collection methods for the diagnosis of urinary tract infections in young children: an observational cohort study. J Paediatr Child Health. 2012; 48(8):659-64. DOI: 10.1111/j.1440-1754.2012.02449.x. View

Tien B, Goh H, Chong K, Bhaduri-Tagore S, Holec S, Dress R . Enterococcus faecalis Promotes Innate Immune Suppression and Polymicrobial Catheter-Associated Urinary Tract Infection. Infect Immun. 2017; 85(12). PMC: 5695114. DOI: 10.1128/IAI.00378-17. View

Walawender L, Hains D, Schwaderer A . Diagnosis and imaging of neonatal UTIs. Pediatr Neonatol. 2019; 61(2):195-200. DOI: 10.1016/j.pedneo.2019.10.003. View

Roberts K . Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics. 2011; 128(3):595-610. DOI: 10.1542/peds.2011-1330. View

Karaca L, Oral A, Kantarci M, Sade R, Ogul H, Bayraktutan U . Comparison of the superb microvascular imaging technique and the color Doppler techniques for evaluating children's testicular blood flow. Eur Rev Med Pharmacol Sci. 2016; 20(10):1947-53. View

Oyaert M, Van Meensel B, Cartuyvels R, Frans J, Laffut W, Vandecandelaere P . Laboratory diagnosis of urinary tract infections: Towards a BILULU consensus guideline. J Microbiol Methods. 2018; 146:92-99. DOI: 10.1016/j.mimet.2018.02.006. View

Stephens G, Akers S, Nguyen H, Woxland H . Evaluation and management of urinary tract infections in the school-aged child. Prim Care. 2015; 42(1):33-41. DOI: 10.1016/j.pop.2014.09.007. View

Yeung C, Sreedhar B, Leung Y, Sit K . Correlation between ultrasonographic bladder measurements and urodynamic findings in children with recurrent urinary tract infection. BJU Int. 2006; 99(3):651-5. DOI: 10.1111/j.1464-410X.2006.06580.x. View

10.

Oelke M, Hofner K, Jonas U, Ubbink D, de la Rosette J, Wijkstra H . Ultrasound measurement of detrusor wall thickness in healthy adults. Neurourol Urodyn. 2006; 25(4):308-17. DOI: 10.1002/nau.20242. View

11.

Wettergren B, Jodal U . Spontaneous clearance of asymptomatic bacteriuria in infants. Acta Paediatr Scand. 1990; 79(3):300-4. DOI: 10.1111/j.1651-2227.1990.tb11460.x. View

12.

Milosevic D, Trkulja V, Turudic D, Batinic D, Spajic B, Tesovic G . Ultrasound bladder wall thickness measurement in diagnosis of recurrent urinary tract infections and cystitis cystica in prepubertal girls. J Pediatr Urol. 2013; 9(6 Pt B):1170-7. DOI: 10.1016/j.jpurol.2013.04.019. View

13.

Bekeris L, Jones B, Walsh M, Wagar E . Urine culture contamination: a College of American Pathologists Q-Probes study of 127 laboratories. Arch Pathol Lab Med. 2008; 132(6):913-7. DOI: 10.5858/2008-132-913-UCCACO. View

14.

Arslan S, Karahan A, Oncu F, Bakdik S, Durmaz M, Tolu I . Diagnostic Performance of Superb Microvascular Imaging and Other Sonographic Modalities in the Assessment of Lateral Epicondylosis. J Ultrasound Med. 2017; 37(3):585-593. DOI: 10.1002/jum.14369. View

15.

Tufano A, Minelli R, Rossi E, Brillantino C, Di Serafino M, Zeccolini M . Inferior epigastric artery pseudoaneurysm secondary to port placement during a robot-assisted laparoscopic radical cystectomy. J Ultrasound. 2020; 24(4):535-538. PMC: 8572286. DOI: 10.1007/s40477-020-00442-1. View

16.

Brillantino C, Rossi E, Bifano D, Minelli R, Tamasi S, Mamone R . An unusual onset of pediatric acute lymphoblastic leukemia. J Ultrasound. 2020; 24(4):555-560. PMC: 8572300. DOI: 10.1007/s40477-020-00461-y. View

17.

Riccabona M . Imaging in childhood urinary tract infection. Radiol Med. 2015; 121(5):391-401. DOI: 10.1007/s11547-015-0594-1. View

18.

Tullus K . Difficulties in diagnosing urinary tract infections in small children. Pediatr Nephrol. 2011; 26(11):1923-6. DOI: 10.1007/s00467-011-1966-y. View

19.

Volikova A, Marshall B, Yin J, Goodwin R, Chow P, Wise M . Structural, biomechanical and hemodynamic assessment of the bladder wall in healthy subjects. Res Rep Urol. 2019; 11:233-245. PMC: 6732741. DOI: 10.2147/RRU.S205383. View

20.

Okarska-Napierala M, Wasilewska A, Kuchar E . Urinary tract infection in children: Diagnosis, treatment, imaging - Comparison of current guidelines. J Pediatr Urol. 2017; 13(6):567-573. DOI: 10.1016/j.jpurol.2017.07.018. View