Pneumococcal Carriage in Children with COVID-19

Overview

Journal Hum Vaccin Immunother

Specialty Allergy & Immunology

Date 2021 Jan 15

PMID 33449815

Citations 8

Authors

Kubra Aykac

Yasemin Ozsurekci

Burcu Ceylan Cura Yayla

Kubra Evren

Sibel Lacinel Gurlevik

Pembe Derin Oygar

Mihriban Yucel

Ayse Esra Karakoc

Alpaslan Alp

Ali Bulent Cengiz

Mehmet Ceyhan

Affiliations

Soon will be listed here.

Abstract

: SARS-CoV-2 is the new virus, and is one of the most important pathogens affecting humans. However, we do not yet know whether these microorganisms interact. Thus, we aimed to evaluate the relationship between and SARS-CoV-2 in pediatric patients.: This study was conducted retrospectively by means of medical records of pediatric patients who were tested for SARS-CoV-2 between March 11 and June 04, 2020, in the University of Health Sciences, Ankara Educating and Training Hospital and Hacettepe University Faculty of Medicine.: We evaluated 829 pediatric patients for and SARS-CoV-2 from their nasopharyngeal specimen. Of 115 children positive for SARS-CoV-2, 32.2% had a positive test, whereas of 714 children negative for SARS-CoV-2, 14.1% had a positive test ( < .01). We compared patients with positive vs. negative SARS-CoV-2 tests according to positivity There were no statistically significant differences in terms of gender, underlying disease, fever, cough, leukocytosis, lymphopenia, increased CRP, increased procalcitonin, findings of chest x-ray, severity of disease, and treatment.: The nasopharyngeal carriage rate in patients with COVID-19 was higher than in non-infected children, while carriage did not affect the course of COVID-19 disease. Pneumococcal vaccination is significant, such that we do not know the outcomes of increased pneumococcal carriage for the upcoming months of pandemic.

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