Molecular Epidemiology of Anaplasmosis in Small Ruminants Along a Human-livestock-wildlife Interface in Uganda

Overview

Journal Heliyon

Specialty Social Sciences

Date 2021 Jan 13

PMID 33437885

Citations 4

Authors

Keneth Iceland Kasozi

Susan Christina Welburn

Gaber El-Saber Batiha

Najat Marraiki

David Paul Nalumenya

Monica Namayanja

Kevin Matama

Kelly Katenta Zalwango

Wycliff Matovu

Gerald Zirintunda

Justine Ekou

Stellamaris Kembabazi

Claire Mack Mugasa

Annah Kitibwa

Dickson Stuart Tayebwa

Simon Peter Musinguzi

Michael Mahero

Ibrahim Ssengendo

Anne Nanteza

Enock Matovu

Ewan Thomas MacLeod

Affiliations

Soon will be listed here.

Abstract

Background: Information as regards the epidemiology of the in small ruminants in several low- and middle-income countries is scarce.

Methods: In this study a total of 712 DNA samples collected from small ruminants were analyzed for and using the and genes respectively. Infection risk was assessed by location, sex and age of the animals and qGIS® was used to construct spatial maps.

Results: The prevalence of spp was 89.1% (95% CI: 77.5-95.9) and 79.1% (95% CI: 75.9-82.1) in ovines and caprines respectively (RR = 1.1, 95% CI: 1.0-1.3); higher than those previously reported in other eastern African countries. The prevalence of was 26.1% and 25.4% for both ovines and caprines respectively with ovines showing significantly higher levels of infection than caprines (P < 0.05). The risk of infections was not affected by age (OR = 1.2, 95% CI: 0.9-1.7) or sex (OR = 1.1, 95% CI: 0.6-2.0). Small ruminants located at the forest edge (<0.3 km) showed higher prevalence than those found inland with infections present in the midland regions associated with increased agricultural activity.

Conclusion: remains a major challenge for small ruminant husbandry in Uganda and infections are under-reported. Policy efforts to prioritize management of for small ruminant health would promote livestock productivity in vulnerable communities, improving livelihoods and ecosystem health.

Citing Articles

Molecular prevalence and associated infection risk factors of tick-borne protozoan and rickettsial blood pathogens in small ruminants.

Abdelsalam M, Felefel W, Fadl S, Bessat M BMC Vet Res. 2023; 19(1):138.

PMID: 37653481 PMC: 10469425. DOI: 10.1186/s12917-023-03702-4.

Species in Africa-A Century of Discovery: A Review on Molecular Epidemiology, Genetic Diversity, and Control.

Kolo A Pathogens. 2023; 12(5).

PMID: 37242372 PMC: 10222256. DOI: 10.3390/pathogens12050702.

Molecular survey of Anaplasma and Ehrlichia species in livestock ticks from Kassena-Nankana, Ghana; with a first report of Anaplasma capra and Ehrlichia minasensis.

Addo S, Baako B, Bentil R, Addae C, Behene E, Asoala V Arch Microbiol. 2023; 205(3):92.

PMID: 36795247 DOI: 10.1007/s00203-023-03430-1.

The first study on the seroprevalence of spp. in small ruminants and assessment of associated risk factors in North Egypt.

Selim A, Attia K, Alsubki R, Albohairy F, Kimiko I, Said M Vet World. 2022; 15(5):1221-1227.

PMID: 35765471 PMC: 9210854. DOI: 10.14202/vetworld.2022.1221-1227.

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