Aflatoxin Detoxification Using Microorganisms and Enzymes

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2021 Jan 13

PMID 33435382

Citations 27

Authors

Yun Guan

Jia Chen

Eugenie Nepovimova

Miao Long

Wenda Wu

Kamil Kuca

Affiliations

Soon will be listed here.

Abstract

Mycotoxin contamination causes significant economic loss to food and feed industries and seriously threatens human health. Aflatoxins (AFs) are one of the most harmful mycotoxins, which are produced by , , and other fungi that are commonly found in the production and preservation of grain and feed. AFs can cause harm to animal and human health due to their toxic (carcinogenic, teratogenic, and mutagenic) effects. How to remove AF has become a major problem: biological methods cause no contamination, have high specificity, and work at high temperature, affording environmental protection. In the present research, microorganisms with detoxification effects researched in recent years are reviewed, the detoxification mechanism of microbes on AFs, the safety of degrading enzymes and reaction products formed in the degradation process, and the application of microorganisms as detoxification strategies for AFs were investigated. One of the main aims of the work is to provide a reliable reference strategy for biological detoxification of AFs.

Citing Articles

Aflatoxin B (AFB) biodegradation by a lignolytic phenoloxidase of Trametes hirsuta.

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Comprehensive review for aflatoxin detoxification with special attention to cold plasma treatment.

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In vitro detoxification of aflatoxin B1 by Lactiplantibacillus plantarum isolated from the north of Iran: A pioneering insights into the origin of fermented beverages.

Eiri A, Kaboosi H, Niknejad F, Ardebili A, Joshaghani H Folia Microbiol (Praha). 2024; .

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Starch can expedite the screening for bacterial aflatoxin degraders.

Sandlin N, Momeni B Sci Rep. 2024; 14(1):31961.

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SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in .

Wu D, Yang C, Yao Y, Ma D, Lin H, Hao L Elife. 2024; 13.

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