Association Between Body Mass Index and Urinary Tract Infection: a Systematic Review and Meta-analysis of Observational Cohort Studies

Overview

Journal Eat Weight Disord

Publisher Springer

Date 2021 Jan 10

PMID 33423153

Citations 10

Authors

Habeeb Alhabeeb

Saeed Baradwan

Hamed Kord-Varkaneh

Shing Cheng Tan

Teck Yew Low

Osama Alomar

Hany Salem

Ismail Abdulrahman Al-Badawi

Ahmed Abu-Zaid

Affiliations

Soon will be listed here.

Abstract

Background And Objective: Very few studies have investigated the relationship between body mass index (BMI) and risk of urinary tract infection (UTI), and conclusions from these available studies have been inconsistent. To resolve this inconsistency, we performed a systematic review and meta-analysis to precisely examine the association between BMI and UTI.

Methods: This meta-analysis was performed based on the PRISMA recommendations. PubMed, Web of Science, Scopus, Embase, and Google Scholar databases were searched for all published observational studies that reported the risk of UTI based on BMI categories up to March 2020.

Results: Fourteen (n = 14) articles comprising 19 studies in different populations met our inclusion criteria. The overall analysis showed a significant increased risk of UTI in subjects affected by obesity vs. individuals without obesity (RR = 1.45; 95% CI: 1.28 - 1.63; I = 94%), and a non-significant increased risk of UTI in subjects who were overweight (RR = 1.03; 95% CI: 0.98 - 1.10; I = 49.6%) and underweight (RR = 0.99; 95% CI: 0.81 - 21; I = 0.0%) when compared to subjects who had normal weight. In the stratified analysis, we showed that obesity increased the risk of UTI in females (RR = 1.63; 95% CI: 1.38 - 1.93) and in subjects below 60 years old (RR = 1.53; 95% CI: 1.33 - 1.75).

Conclusion: This systematic review and meta-analysis recognized a significant relationship between BMI and incidence of UTI in obese vs. non-obese subjects, as well as in females and in individuals below 60 years old.

Citing Articles

Predictive Factors for Urinary Tract Infections in Patients with Type 2 Diabetes.

Sorescu T, Cosnita A, Braha A, Timar R, Timar B, Licker M J Clin Med. 2025; 13(24.

PMID: 39768552 PMC: 11727733. DOI: 10.3390/jcm13247628.

Can the Total Body Water and Total Fat Mass Predict Kidney Stone Recurrence in Overweight and Obese Patients?.

Pricop C, Ivanuta M, Nikolic M, Ivanuta A, Botnariu G, Stan A Cureus. 2024; 16(11):e73367.

PMID: 39659337 PMC: 11631159. DOI: 10.7759/cureus.73367.

Association between body mass index and urinary tract infections: A cross-sectional investigation of the PERSIAN Guilan cohort study.

Taramian S, Joukar F, Maroufizadeh S, Hassanipour S, Sheida F, Mansour-Ghanaei F Obes Sci Pract. 2024; 10(5):e70013.

PMID: 39429540 PMC: 11490256. DOI: 10.1002/osp4.70013.

Plant-based diets and urological health.

Loeb S, Borin J, Venigalla G, Narasimman M, Gupta N, Cole A Nat Rev Urol. 2024; .

PMID: 39375468 DOI: 10.1038/s41585-024-00939-y.

Characteristics of Nursing Homes with High Rates of Urinary Tract Infections among Their Residents with Obesity.

Felix H, Brown C, Narcisse M, Vincenzo J, Andersen J, Weech-Maldonado R Urol Nurs. 2024; 46(3):273-303.

PMID: 38774393 PMC: 11105761. DOI: 10.7257/2168-4626.2023.43.6.273.

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