Pharmacological Activity of Eriodictyol: The Major Natural Polyphenolic Flavanone

Overview

Journal Evid Based Complement Alternat Med

Specialty Rehabilitation Medicine

Date 2021 Jan 8

PMID 33414838

Citations 25

Authors

Zirong Deng

Sabba Hassan

Muhammad Rafiq

Hongshui Li

Yang He

Yi Cai

Xi Kang

Zhaoguo Liu

Tingdong Yan

Affiliations

Soon will be listed here.

Abstract

Eriodictyol is a flavonoid that belongs to a subclass of flavanones and is widespread in citrus fruits, vegetables, and medicinally important plants. Eriodictyol has been anticipated to explain the method of its activity via multiple cellular signaling cascades. Eriodictyol is an effective natural drug source to maintain higher health standards due to its excellent therapeutic roles in neuroprotection, cardioprotective activity, hepatoprotective activity, antidiabetes and obesity, and skin protection and having highly analgesic, antioxidant, and anti-inflammatory effects, antipyretic and antinociceptive actions, antitumor activity, and much more. This review aims to highlight the modes of action of eriodictyol against various diseases via multiple cellular signaling pathways.

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