Recent Advances in Aptamer-Based Biosensors for Detection of

Overview

Journal Front Microbiol

Specialty Microbiology

Date 2021 Jan 8

PMID 33414776

Citations 11

Authors

Xin Zheng

Shunxiang Gao

Jihong Wu

Xiaobo Hu

Affiliations

Soon will be listed here.

Abstract

Increasing concerns about nosocomial infection, food and environmental safety have prompted the development of rapid, accurate, specific and ultrasensitive methods for the early detection of critical pathogens. is one of the most common pathogens that cause infection. It is ubiquitous in nature, being found in water, soil, and food, and poses a great threat to public health. The conventional detection technologies are either time consuming or readily produce false positive/negative results, which makes them unsuitable for early diagnosis and spot detection of . To circumvent these drawbacks, many efforts have been made to develop biosensors using aptamers as bio-recognition elements. Various aptamer-based biosensors for clinical diagnostics, food, and environmental monitoring of have been developed in recent years. In this review, we focus on the latest advances in aptamer-based biosensors for detection of . Representative biosensors are outlined according to their sensing mechanisms, which include optical, electrochemical and other signal transduction methods. Possible future trends in aptamer biosensors for pathogen detection are also outlined.

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