Anxiety and Depression Symptoms, the Recovery from Symptoms, and Loneliness Before and After the COVID-19 Outbreak Among the General Population: Findings from a Dutch Population-based Longitudinal Study

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2021 Jan 7

PMID 33411843

Citations 66

Authors

Peter G van der Velden

Philip Hyland

Carlo Contino

Hans-Martin von Gaudecker

Ruud Muffels

Marcel Das

Affiliations

Soon will be listed here.

Abstract

Objectives: Examine the effects of the COVID-19 pandemic on the mental health and loneliness in the general population. More specifically, the study focused on prevalence of anxiety and depression symptoms, the extent to which individuals with existing symptoms recovered or not, the prevalence of subtypes of loneliness, and the extent to which loneliness before and during this pandemic was associated with anxiety and depression symptoms.

Methods: Data was extracted from the longitudinal LISS panel, based on a probability sample of the Dutch population, with assessments on loneliness in October 2019 (T1) and June 2020 (T4), and anxiety and depression symptoms in November 2019 (T2), March 2020 (T3) and June 2020 (T4; Ntotal = 4,084). Loneliness was examined with the De Jong Gierveld Loneliness Scale and anxiety and depression symptoms with the Mental Health Inventory (MHI-5).

Results: Repeated measures multivariate logistic regression analyses (RMMLRA) showed a statistical significant lower prevalence of anxiety and depression symptoms after the outbreak (T4 = 15.3%) than before (T2 = 16.8%) and during the COVID-19 outbreak (T3 = 17.2%). According to the Reliable Change Index, the distribution of recovery categories (remission, improvement, unchanged and worsening symptoms) after the outbreak did not differ significantly from the distribution of these categories before the outbreak. RMMLRA revealed that the prevalence of emotional loneliness increased significantly after the outbreak (T1 = 18.4%, T4 = 24.8%). Among individuals who were not lonely before and after the outbreak the prevalence of symptoms decreased significantly (T2 = 7.0%, T4 = 4.4%) and, likewise, among those who were not lonely anymore after the outbreak (T2 = 21.5%, T4 = 14.5%). However, the prevalence of symptoms increased significantly among those who became lonely during the pandemic (T2 = 17.9%, T4 = 26.3%).

Conclusions: Findings suggest that this pandemic did not negatively affect the prevalence of anxiety and depression symptoms nor the normal recovery of symptoms among the general population during the first four months, but that emotional loneliness increased.

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References

Vindegaard N, Benros M . COVID-19 pandemic and mental health consequences: Systematic review of the current evidence. Brain Behav Immun. 2020; 89:531-542. PMC: 7260522. DOI: 10.1016/j.bbi.2020.05.048. View

Rains L, Johnson S, Barnett P, Steare T, Needle J, Carr S . Early impacts of the COVID-19 pandemic on mental health care and on people with mental health conditions: framework synthesis of international experiences and responses. Soc Psychiatry Psychiatr Epidemiol. 2020; 56(1):13-24. PMC: 7429938. DOI: 10.1007/s00127-020-01924-7. View

Palgi Y, Shrira A, Ring L, Bodner E, Avidor S, Bergman Y . The loneliness pandemic: Loneliness and other concomitants of depression, anxiety and their comorbidity during the COVID-19 outbreak. J Affect Disord. 2020; 275:109-111. PMC: 7330569. DOI: 10.1016/j.jad.2020.06.036. View

Costa M, Pavlo A, Reis G, Ponte K, Davidson L . COVID-19 Concerns Among Persons With Mental Illness. Psychiatr Serv. 2020; 71(11):1188-1190. DOI: 10.1176/appi.ps.202000245. View

Daly M, Sutin A, Robinson E . Depression reported by US adults in 2017-2018 and March and April 2020. J Affect Disord. 2020; 278:131-135. PMC: 7490280. DOI: 10.1016/j.jad.2020.09.065. View

Twenge J, Joiner T . U.S. Census Bureau-assessed prevalence of anxiety and depressive symptoms in 2019 and during the 2020 COVID-19 pandemic. Depress Anxiety. 2020; 37(10):954-956. PMC: 7405486. DOI: 10.1002/da.23077. View

Luchetti M, Lee J, Aschwanden D, Sesker A, Strickhouser J, Terracciano A . The trajectory of loneliness in response to COVID-19. Am Psychol. 2020; 75(7):897-908. PMC: 7890217. DOI: 10.1037/amp0000690. View

Hyland P, Shevlin M, McBride O, Murphy J, Karatzias T, Bentall R . Anxiety and depression in the Republic of Ireland during the COVID-19 pandemic. Acta Psychiatr Scand. 2020; 142(3):249-256. DOI: 10.1111/acps.13219. View

Smith B, Lim M . How the COVID-19 pandemic is focusing attention on loneliness and social isolation. Public Health Res Pract. 2020; 30(2). DOI: 10.17061/phrp3022008. View

10.

Hao F, Tan W, Jiang L, Zhang L, Zhao X, Zou Y . Do psychiatric patients experience more psychiatric symptoms during COVID-19 pandemic and lockdown? A case-control study with service and research implications for immunopsychiatry. Brain Behav Immun. 2020; 87:100-106. PMC: 7184991. DOI: 10.1016/j.bbi.2020.04.069. View

11.

Heinrich L, Gullone E . The clinical significance of loneliness: a literature review. Clin Psychol Rev. 2006; 26(6):695-718. DOI: 10.1016/j.cpr.2006.04.002. View

12.

Bu F, Steptoe A, Fancourt D . Who is lonely in lockdown? Cross-cohort analyses of predictors of loneliness before and during the COVID-19 pandemic. Public Health. 2020; 186:31-34. PMC: 7405905. DOI: 10.1016/j.puhe.2020.06.036. View

13.

Xiong J, Lipsitz O, Nasri F, Lui L, Gill H, Phan L . Impact of COVID-19 pandemic on mental health in the general population: A systematic review. J Affect Disord. 2020; 277:55-64. PMC: 7413844. DOI: 10.1016/j.jad.2020.08.001. View

14.

Kozloff N, Mulsant B, Stergiopoulos V, Voineskos A . The COVID-19 Global Pandemic: Implications for People With Schizophrenia and Related Disorders. Schizophr Bull. 2020; 46(4):752-757. PMC: 7197583. DOI: 10.1093/schbul/sbaa051. View

15.

Jacobson N, Truax P . Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. J Consult Clin Psychol. 1991; 59(1):12-9. DOI: 10.1037//0022-006x.59.1.12. View

16.

Philip K, Polkey M, Hopkinson N, Steptoe A, Fancourt D . Social isolation, loneliness and physical performance in older-adults: fixed effects analyses of a cohort study. Sci Rep. 2020; 10(1):13908. PMC: 7431531. DOI: 10.1038/s41598-020-70483-3. View

17.

Killgore W, Cloonan S, Taylor E, Miller M, Dailey N . Three months of loneliness during the COVID-19 lockdown. Psychiatry Res. 2020; 293:113392. PMC: 7430289. DOI: 10.1016/j.psychres.2020.113392. View

18.

Sheridan A, Andersen A, Hansen E, Johannesen N . Social distancing laws cause only small losses of economic activity during the COVID-19 pandemic in Scandinavia. Proc Natl Acad Sci U S A. 2020; 117(34):20468-20473. PMC: 7456178. DOI: 10.1073/pnas.2010068117. View

19.

Hawkley L, Cacioppo J . Loneliness matters: a theoretical and empirical review of consequences and mechanisms. Ann Behav Med. 2010; 40(2):218-27. PMC: 3874845. DOI: 10.1007/s12160-010-9210-8. View

20.

van der Velden P, Contino C, Das M, van Loon P, Bosmans M . Anxiety and depression symptoms, and lack of emotional support among the general population before and during the COVID-19 pandemic. A prospective national study on prevalence and risk factors. J Affect Disord. 2020; 277:540-548. PMC: 7438386. DOI: 10.1016/j.jad.2020.08.026. View