Review on Experimental Study and Clinical Application of Low-intensity Pulsed Ultrasound in Inflammation

Overview

Journal Quant Imaging Med Surg

Specialty Radiology

Date 2021 Jan 4

PMID 33392043

Citations 13

Authors

Maosheng Xu

Liang Wang

Senmin Wu

Yanyan Dong

Xiu Chen

Shijia Wang

Xiuyun Li

Chunpeng Zou

Affiliations

Soon will be listed here.

Abstract

Low-intensity pulsed ultrasound (LIPUS), as physical therapy, is widely used in both research and clinical settings. It induces multiple bioeffects, such as alleviating pain, promoting tissue repair, and shortening disease duration. LIPUS can also mediate inflammation. This paper reviews the application of LIPUS in inflammation and discusses the underlying mechanism. In basic experiments, LIPUS can regulate inflammatory responses at the cellular level by affecting some signaling pathways. In a clinical trial, LIPUS has been shown to alleviate inflammatory responses efficiently. As a cheap, safe, and convenient physical method, LIPUS is promising as anti-inflammatory therapy.

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