Placental Thickness Correlates with Placenta Accreta Spectrum (PAS) Disorder in Women with Placenta Previa

Overview

Journal Abdom Radiol (NY)

Publisher Springer

Specialties Gastroenterology
Radiology

Date 2021 Jan 3

PMID 33388802

Citations 3

Authors

Yan Li

Hailey H Choi

Ruth Goldstein

Liina Poder

Priyanka Jha

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the association of placental thickness with placenta accreta spectrum disorder in placenta previa.

Methods: In this IRB-approved, retrospective study, ultrasound (US) reports were retrospectively queried for keyword previa. US performed closest to mid-gestation were included. Three measurements were performed at the thickest portion of the placenta on longitudinal transabdominal images. Operative reports and surgical pathology were used as the reference standard. Statistical analysis was performed using unpaired T-tests and receiver operating curve (ROC) analysis.

Results: Sixty-five patients with placenta previa were included: 38 with PAS disorder and 27 without PAS disorder, clinically or pathologically. 38/38 (100%) patients of PAS group and 16/27 (59.3%) patients of non-PAS group had history of prior cesarean section. The average placental thickness was 4.3 cm (range 1.8 cm to 7.8 cm) for PAS group and 3.0 cm (range 0.6 cm to 5.3 cm) for non-PAS group (p < 0.001). Placental thickness in patients without PAS disorder and history of prior cesarean section was 3.1 (± 1.1) cm. This was statistically different from patients who had history of prior cesarean section with PAS diagnosis (4.3 cm, P<0.01). Using ROC analysis, a threshold measurement of 4.5 cm leads to sensitivity of 50% and specificity of 96%.

Conclusion: Our results demonstrate that among women with placenta previa, increased placental thickness at lower uterine segment correlates with placenta accreta spectrum disorder. A threshold of 4.5 cm can be useful for screening patients with placenta previa and risks factors for PAS.

Citing Articles

Risk factors of emergency cesarean section in pregnant women with severe placenta accreta spectrum: a retrospective cohort study.

Zhao H, Li X, Yang S, Liu T, Zhan J, Zou J Front Med (Lausanne). 2023; 10:1195546.

PMID: 37502363 PMC: 10370267. DOI: 10.3389/fmed.2023.1195546.

Diagnostic Accuracy of Placental Thickness in Lower Uterine Segment Measured by Ultrasound in Prediction of Placenta Accreta Spectrum in Patients with Placenta Previa. A Diagnostic Test Accuracy Study.

Elmaraghy A, Taha Fayed S, Abd ElHamid Ali M, Ali Hassanien M, Mohamed Mamdouh A Int J Womens Health. 2023; 15:311-320.

PMID: 36814526 PMC: 9940499. DOI: 10.2147/IJWH.S399520.

Correlation of placental thickness and placenta percreta in patients with placenta previa: findings from MRI.

Lu T, Wang Y, Guo A, Deng Y, Wu C, Li X Abdom Radiol (NY). 2022; 47(12):4237-4244.

PMID: 36114883 DOI: 10.1007/s00261-022-03676-1.

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