Association Between the Microsatellite Ap243, AC117 and SV185 Polymorphisms and Disease in the Dark Forest Bee
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The microsporidian parasites, primarily , remain critical threats to the health of the honey bee . One promising intervention approach is the breeding of -resistant honey bee colonies using molecular technologies, for example marker-assisted selection (MAS). For this, specific genetic markers used in bee selection should be developed. The objective of the paper is to search for associations between some microsatellite markers and disease in a dark forest bee . For the dark forest bee, the most promising molecular genetic markers for determining resistance to nosemosis are microsatellite loci AC117, Ap243 and SV185, the alleles of which ("177", "263" and "269", respectively) were associated with a low level of infection. This article is the first associative study aimed at finding DNA loci of resistance to nosemosis in the dark forest bee. Nevertheless, microsatellite markers identified can be used to predict the risk of developing the disease.
Cilia G, Nanetti A Vet Sci. 2021; 8(7).
PMID: 34357919 PMC: 8310213. DOI: 10.3390/vetsci8070127.