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Unraveling the Role of Fibroblasts, FGF5 and FGFR2 in HER2-targeted Therapies Resistance and Tumor Progression

Overview
Journal Oncotarget
Specialty Oncology
Date 2020 Dec 21
PMID 33346249
Citations 1
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References
1.
Zervantonakis I, Poskus M, Scott A, Selfors L, Lin J, Dillon D . Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways. Proc Natl Acad Sci U S A. 2020; 117(28):16500-16508. PMC: 7368275. DOI: 10.1073/pnas.2000648117. View

2.
Merz V, Zecchetto C, Simionato F, Cavaliere A, Casalino S, Pavarana M . A phase II trial of the FGFR inhibitor pemigatinib in patients with metastatic esophageal-gastric junction/gastric cancer trastuzumab resistant: the FiGhTeR trial. Ther Adv Med Oncol. 2020; 12:1758835920937889. PMC: 7346700. DOI: 10.1177/1758835920937889. View

3.
Klemm F, Joyce J . Microenvironmental regulation of therapeutic response in cancer. Trends Cell Biol. 2014; 25(4):198-213. PMC: 5424264. DOI: 10.1016/j.tcb.2014.11.006. View

4.
Gascard P, Tlsty T . Carcinoma-associated fibroblasts: orchestrating the composition of malignancy. Genes Dev. 2016; 30(9):1002-19. PMC: 4863733. DOI: 10.1101/gad.279737.116. View

5.
Piro G, Carbone C, Cataldo I, Di Nicolantonio F, Giacopuzzi S, Aprile G . An FGFR3 Autocrine Loop Sustains Acquired Resistance to Trastuzumab in Gastric Cancer Patients. Clin Cancer Res. 2016; 22(24):6164-6175. DOI: 10.1158/1078-0432.CCR-16-0178. View