Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2020 Dec 18

PMID 33335907

Citations 14

Authors

Denise Rotta

Angelo Fassio

Maurizio Rossini

Alessandro Giollo

Ombretta Viapiana

Giovanni Orsolini

Eugenia Bertoldo

Davide Gatti

Giovanni Adami

Affiliations

Soon will be listed here.

Abstract

Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective.

Citing Articles

The Paradox of Osteoporosis in Spondyloarthropathies.

Angelopoulos A, Kouverianos I, Daoussis D Mediterr J Rheumatol. 2025; 35(Suppl 3):528-533.

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Anthocyanins from a new hybrid sweet potato peel cultivated in Northern Thailand mitigate LPS-induced inflammation and RANKL-induced osteoporosis by regulating ROS-mediated pathways.

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Correlation between Trabecular Bone Score and Homocysteine Level in Rheumatoid Arthritis Patients on Anti-TNF Inhibitors.

Ionita-Radu F, Nicolau I, Petrache O, Groseanu M, Bojinca V, Negru M Life (Basel). 2024; 14(4).

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Machine learning to characterize bone biomarkers profile in rheumatoid arthritis.

Adami G, Fassio A, Rossini M, Benini C, Bixio R, Rotta D Front Immunol. 2023; 14:1291727.

PMID: 38022514 PMC: 10665911. DOI: 10.3389/fimmu.2023.1291727.

Factors associated with radiographic progression in rheumatoid arthritis starting biological diseases modifying anti-rheumatic drugs (bDMARDs).

Adami G, Fassio A, Pistillo F, Benini C, Viapiana O, Rossini M Ther Adv Musculoskelet Dis. 2023; 15:1759720X231174534.

PMID: 37780955 PMC: 10540567. DOI: 10.1177/1759720X231174534.

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