Acute Disseminated Encephalomyelitis (ADEM) Associated with COVID-19

Overview

Journal BMJ Case Rep

Specialty General Medicine

Date 2020 Dec 15

PMID 33318286

Citations 26

Authors

Lawrence Langley

Claudia Zeicu

Louise Whitton

Mathilde Pauls

Affiliations

Soon will be listed here.

Abstract

A 53-year-old man admitted to the critical care secondary to respiratory failure due to COVID-19 developed agitation and global hypotonia. Brain MRI revealed bilateral hyperintense lesions throughout the brain and cerebrospinal fluid identified oligoclonal bands. Intravenous high-dose glucocorticoids were administered followed by an oral tapering dose and the patient clinically improved. Acute disseminated encephalomyelitis should be considered in patients with COVID-19 who present with altered mentation and polyfocal neurological deficits.

Citing Articles

Cognitive and psychopathological outcomes in acute disseminated encephalomyelitis.

Kazzi C, Alpitsis R, OBrien T, Malpas C, Monif M BMJ Neurol Open. 2024; 6(1):e000640.

PMID: 38736586 PMC: 11085806. DOI: 10.1136/bmjno-2024-000640.

The Occurrence of Acute Disseminated Encephalomyelitis in SARS-CoV-2 Infection/Vaccination: Our Experience and a Systematic Review of the Literature.

Stoian A, Bajko Z, Stoian M, Cioflinc R, Niculescu R, Arbanasi E Vaccines (Basel). 2023; 11(7).

PMID: 37515041 PMC: 10385010. DOI: 10.3390/vaccines11071225.

Association of acute disseminated encephalomyelitis (ADEM) and COVID-19 in a pediatric patient.

Chen L Free Neuropathol. 2023; 2.

PMID: 37284632 PMC: 10209852. DOI: 10.17879/freeneuropathology-2021-3388.

Acute Disseminated Encephalomyelitis Post COVID-19 Pneumonia.

Alqarni A, Aljafari D, AlZahrani F, Alharthi A, Alhubayshi M Cureus. 2023; 15(2):e34615.

PMID: 36891024 PMC: 9986969. DOI: 10.7759/cureus.34615.

Newly diagnosed autoimmune Addison's disease in a patient with COVID-19 with autoimmune disseminated encephalomyelitis.

Beshay L, Wei K, Yang Q BMJ Case Rep. 2023; 15(12).

PMID: 36593594 PMC: 9723877. DOI: 10.1136/bcr-2022-250749.

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