Molecular Imaging in Tracking Cancer Stem Cells: A Review

Overview

Journal Med J Islam Repub Iran

Specialty General Medicine

Date 2020 Dec 11

PMID 33306061

Citations 1

Authors

Hamed Ghaffari

Mohammad Reza Atashzar

Hamid Abdollahi

Affiliations

Soon will be listed here.

Abstract

Cancer stem cells (CSCs) have critical roles in tumor development, progression, and recurrence. They are responsible for current cancer treatment failure and remain questionable for the design and development of new therapeutic strategies. With this issue, medical imaging provides several clues for finding biological mechanisms and strategies to treat CSCs. This review aims to summarize current molecular imaging approaches for detecting CSCs. In addition, some promising issues for CSCs finding and explaining biological mechanisms have been addressed. Among the molecular imaging approaches, modalities including Magnetic resonance imaging (MRI) and positron emission tomography (PET) have the greatest roles and several new approaches such as optical imaging are in progress.

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