COVID-19 Vaccine Race: Watch Your Step for Cancer Patients

Overview

Journal Br J Cancer

Specialty Oncology

Date 2020 Dec 8

PMID 33288844

Citations 18

Authors

Raphaelle Fanciullino

Joseph Ciccolini

Gerard Milano

Affiliations

Soon will be listed here.

Abstract

Patients with cancer should benefit from COVID-19 vaccination. Some of the most advanced vaccine candidates are mRNAs encapsulated into lipid carriers, and small liposomes are expected to accumulate in tumour tissues through the enhanced and permeation retention effect. However, to what extent solid tumours could take up a significant part of the vaccine dose as well remains unknown. This calls for a careful evaluation of the efficacy of these promising mRNA COVID-19 vaccines administered as lipid carriers for patients with solid tumours, including a possible re-appraisal of the dosing for optimal protection of this specific and frail population.

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