COVID-19 in the Elderly People and Advances in Vaccination Approaches

Overview

Journal Hum Vaccin Immunother

Specialty Allergy & Immunology

Date 2020 Dec 3

PMID 33270497

Citations 29

Authors

Kuldeep Dhama

Shailesh Kumar Patel

Senthilkumar Natesan

Kranti Suresh Vora

Mohd Iqbal Yatoo

Ruchi Tiwari

Shailendra K Saxena

Karam Pal Singh

Rajendra Singh

Yashpal Singh Malik

Affiliations

Soon will be listed here.

Abstract

The rapid worldwide spread of the COVID-19 pandemic, caused by the newly emerged severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in tens of millions of infections and over one million deaths. SARS-CoV-2 infection affects all age groups; however, those over 60 years old are affected more severely. Moreover, pre-existing co-morbidities result in higher COVID-19-associated mortality in the geriatric population. This article highlights the associated risk factors of SARS-CoV-2 infection in older people and progress in developing COVID-19 vaccines, especially for efficient vaccination of the older population. There is also a summary of immunomodulatory and immunotherapeutic approaches to ameliorate the outcome of COVID-19 in older individuals.

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