Prenatal Exposure to Preeclampsia As a Risk Factor for Long-term Endocrine Morbidity of the Offspring
Overview
Affiliations
: To analyze preeclampsia as a risk factor for pediatric endocrine disease. : A population-based cohort analysis comparing the risk of endocrine morbidity of children born between 1991-2014 to mothers with and without preeclampsia. : The study included 253,808 deliveries. Exposed offspring had significantly more endocrine hospitalizations (0.7% vs 0.4%; < 0.001), specifically obesity (0.4% vs 0.2%, < 0.001). While controlling for confounders, the exposed offspring had significantly more endocrine morbidity (OR 1.433 95% CI 1.115-1.841 = 0.005). : Preeclampsia is an independent risk factor for long-term endocrine disease of the offspring, specifically obesity.
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