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Prenatal Exposure to Preeclampsia As a Risk Factor for Long-term Endocrine Morbidity of the Offspring

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Publisher Informa Healthcare
Date 2020 Dec 2
PMID 33264044
Citations 4
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Abstract

: To analyze preeclampsia as a risk factor for pediatric endocrine disease. : A population-based cohort analysis comparing the risk of endocrine morbidity of children born between 1991-2014 to mothers with and without preeclampsia. : The study included 253,808 deliveries. Exposed offspring had significantly more endocrine hospitalizations (0.7% vs 0.4%;  < 0.001), specifically obesity (0.4% vs 0.2%,  < 0.001). While controlling for confounders, the exposed offspring had significantly more endocrine morbidity (OR 1.433 95% CI 1.115-1.841  = 0.005). : Preeclampsia is an independent risk factor for long-term endocrine disease of the offspring, specifically obesity.

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