Treatment of Tibial Dyschondroplasia with Traditional Chinese Medicines: "Lesson and Future Directions"

Overview

Journal Poult Sci

Publisher Elsevier

Specialty Veterinary Medicine

Date 2020 Nov 29

PMID 33248557

Citations 7

Authors

Hui Zhang

Yajing Wang

Khalid Mehmood

Yung-Fu Chang

Zhaoxin Tang

Ying Li

Affiliations

Soon will be listed here.

Abstract

Tibial dyschondroplasia (TD) is a metabolic tibiotarsal bone disease in rapidly growing birds throughout the world, which is characterized by gait disorders, reduced growth, and in an unrecoverable lameness in many cases. The short production cycle in chickens, long metabolism cycle in most of the drugs with the severe drug residue, and high treatment cost severely restrict the enthusiasm for the treatment of TD. Traditional Chinese medicine (TCM) has been used for the prevention, treatment, and cure of avian bone diseases. Previously, a couple of traditional Chinese medicines has been reported being useful in treating TD. This review will discuss the TCM used in TD and the alternative TCM to treat TD. Selecting a TCM approach and its pharmacologic effects on TD chickens mainly focused on the differentiation, proliferation, and apoptosis of chondrocytes, angiogenesis, matrix metabolism, oxidative damage, cytokines, and calcification of cartilage in tibia.

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