Assessment of Diabetic Retinopathy Vascular Density Maps

Overview

Journal Clin Ophthalmol

Publisher Dove Medical Press

Specialty Ophthalmology

Date 2020 Nov 26

PMID 33239860

Citations 5

Authors

Passant Sayed Saif

Abd El-Rahman Gaber Salman

Norhan Amr Hassan Omran

Yousra Ahmed Thabet Farweez

Affiliations

Soon will be listed here.

Abstract

Purpose: Optical coherence tomography (OCT) and OCTA were used for qualitative and quantitative assessment of retinal vascular density in superficial capillary plexus, deep capillary plexus, foveal avascular zone, and choroidal vascular density map.

Patients And Methods: This study included 64 eyes. Diabetics and control groups were recruited from an internal medicine clinic at Misr University for Science and Technology Hospital and asked to participate in this study. This study was designed as an observational and cross-sectional study in the period from 8/2018 to 8/2019.

Results: There was a decrease in choroidal vascular density in diabetic patients. There was a decrease in retinal thickness in diabetic patients and there were no signiﬁcant differences in the retinal thickness between control subjects and patients with non-diabetic retinopathy (NDR).

Conclusion: Our study suggests that OCTA can identify preclinical DR before the manifestation of clinically apparent retinopathy. Our ﬁndings also highlight the potential role of OCTA in monitoring and quantifying retinal vascular alterations in diabetics.

Citing Articles

Quantitative Analysis of Early Retinal Changes and OCT Parameters in Diabetic Subjects with and Without Retinopathy.

Aldakhil S, Challa N, Alhoshan S, Abohaimed F, Alnasser B, Almuhawas H Diagnostics (Basel). 2025; 15(4).

PMID: 40002602 PMC: 11854782. DOI: 10.3390/diagnostics15040451.

Sub-Clinical Regional Macular Changes in Self-Reported Diabetic Subjects: Vascular and Retinal Layer Analysis Using Swept-Source OCT.

Challa N, Alghamdi W, Alluwimi M, Alshammeri S Diabetes Metab Syndr Obes. 2025; 18:363-372.

PMID: 39931374 PMC: 11809218. DOI: 10.2147/DMSO.S504882.

The role of optical coherence tomography angiography in assessing diabetic choroidopathy: a systematic review.

Nowroozzadeh M, Bagheri M Int J Retina Vitreous. 2025; 11(1):10.

PMID: 39891221 PMC: 11786548. DOI: 10.1186/s40942-024-00618-5.

Macular Vascularity and Ganglion Cell Complex Parameters in the Young Adults with Myopia and Progressive Myopia.

Malyszczak A, Zyto M, Przezdziecka-Dolyk J, Misiuk-Hojlo M Clin Ophthalmol. 2023; 17:561-570.

PMID: 36817636 PMC: 9930574. DOI: 10.2147/OPTH.S389963.

Quantitative measures of the vascular and neural components of the retina in adult individuals with congenital and untreated growth hormone deficiency.

Menezes N, Barros-Oliveira C, Salvatori R, Gois V, Marinho C, Oliveira C Int J Retina Vitreous. 2022; 8(1):72.

PMID: 36183116 PMC: 9526970. DOI: 10.1186/s40942-022-00408-x.

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