Medicinal Activities and Nanomedicine Delivery Strategies for Oil and Its Molecular Components

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2020 Nov 24

PMID 33228061

Citations 7

Authors

Bo Kyeong Yoon

Zheng Yi Lim

Won-Yong Jeon

Nam-Joon Cho

Jeong Hoon Kim

Joshua A Jackman

Affiliations

Soon will be listed here.

Abstract

oil (BJO) is widely used in traditional Chinese medicine to treat various types of cancer and inflammatory diseases. There is significant interest in understanding the medicinal activities of BJO and its molecular components, especially quassinoids, and in exploring how they can be incorporated into nanomedicine delivery strategies for improved application prospects. Herein, we cover the latest progress in developing different classes of drug delivery vehicles, including nanoemulsions, liposomes, nanostructured lipid carriers, and spongosomes, to encapsulate BJO and purified quassinoids. An introduction to the composition and medicinal activities of BJO and its molecular components, including quassinoids and fatty acids, is first provided. Application examples involving each type of drug delivery vehicle are then critically presented. Future opportunities for nanomedicine delivery strategies in the field are also discussed and considered within the context of translational medicine needs and drug development processes.

Citing Articles

The Potential of Natural Oils to Improve Inflammatory Bowel Disease.

Zhou Y, Wang D, Duan H, Zhou S, Guo J, Yan W Nutrients. 2023; 15(11).

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oil alleviates intestinal mucosal injury induced by chemotherapeutic agent 5-fluorouracil in mice.

Zheng X, Mai L, Xu Y, Wu M, Chen L, Chen B Front Pharmacol. 2023; 14:1136076.

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Chinese Herbal Medicine for Primary Liver Cancer Therapy: Perspectives and Challenges.

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Major Constituents From and Their Pharmacological Actions.

Zhang J, Xu H, Dou Y, Huang Q, Xian Y, Lin Z Front Pharmacol. 2022; 13:853119.

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Efficacy and Safety of Oil Emulsion Injection in the Treatment of Gastric Cancer: A Systematic Review and Meta-Analysis.

Wang X, Wang H, Cao L, Wu J, Lu T, Li S Front Nutr. 2021; 8:784164.

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