Clinical Disorders of Phosphorus Metabolism

Overview

Journal West J Med

Specialty General Medicine

Date 1987 Nov 1

PMID 3321712

Citations 5

Authors

G C Yu

D B Lee

Affiliations

Soon will be listed here.

Abstract

Deranged phosphorus metabolism is commonly encountered in clinical medicine. Disturbances in phosphate intake, excretion and transcellular shift account for the abnormal serum levels. As a result of the essential role played by phosphate in intracellular metabolism, the clinical manifestations of hypophosphatemia and hyperphosphatemia are extensive. An understanding of the pathophysiology of various phosphate disorders is helpful in guiding therapeutic decisions.

Citing Articles

Dietary supplementation with L-lysine affects body weight and blood hematological and biochemical parameters in rats.

Xiao C, Wood C, Bertinato J Mol Biol Rep. 2018; 46(1):433-442.

PMID: 30488372 DOI: 10.1007/s11033-018-4492-1.

Dystrophic mineralization of the arterial fibrovascular tissue associated with a vitamin D hypervitaminosis in an 8-year-old female Alpaca ().

Tavella A, Stefani A, Zanardello C, Bettini A, Gauly M, Zanolari P Ir Vet J. 2016; 69:19.

PMID: 28018578 PMC: 5160019. DOI: 10.1186/s13620-016-0078-1.

Forensic application of ESEM and XRF-EDS techniques to a fatal case of sodium phosphate enema intoxication.

Viel G, Cecchetto G, Fabbri L, Furlan C, Ferrara S, Montisci M Int J Legal Med. 2009; 123(4):345-50.

PMID: 19347348 DOI: 10.1007/s00414-009-0344-9.

Respiratory failure requiring extracorporeal membrane oxygenation after sodium phosphate enema intoxication.

Everman D, Nitu M, Jacobs B Eur J Pediatr. 2003; 162(7-8):517-519.

PMID: 12768416 DOI: 10.1007/s00431-002-0987-8.

Clinical significance in alcoholic patients of commonly encountered laboratory test results.

Magarian G, Lucas L, Kumar K West J Med. 1992; 156(3):287-94.

PMID: 1595246 PMC: 1003236.

References

Shackney S, Hasson J . Precipitous fall in serum calcium, hypotension, and acute renal failure after intravenous phosphate therapy for hypercalcemia. Report of two cases. Ann Intern Med. 1967; 66(5):906-16. DOI: 10.7326/0003-4819-66-5-906. View

BIJVOET O, MAJOOR C . THE RENAL TUBULAR REABSORPTION OF PHOSPHATE IN THYROTOXICOSIS. Clin Chim Acta. 1965; 11:181-3. DOI: 10.1016/0009-8981(65)90213-5. View

Slatopolsky E, Robson A, ELKAN I, Bricker N . Control of phosphate excretion in uremic man. J Clin Invest. 1968; 47(8):1865-74. PMC: 297347. DOI: 10.1172/JCI105877. View

Anderson D, Peters T, Stewart W . Association of hypokalaemia and hypophosphataemia. Br Med J. 1969; 4(5680):402-3. PMC: 1629773. DOI: 10.1136/bmj.4.5680.402. View

BIJVOET O, MORGAN D, FOURMAN P . The assessment of phosphate reabsorption. Clin Chim Acta. 1969; 26(1):15-24. DOI: 10.1016/0009-8981(69)90280-0. View

MASSARA F, Camanni F . Propranolol block of adrenaline-induced hypophosphataemia in man. Clin Sci. 1970; 38(2):245-50. DOI: 10.1042/cs0380245. View

Pollock R, Watson R . Malignant hyperthermia associated with hypocalcemia. Anesthesiology. 1971; 34(2):188-94. DOI: 10.1097/00000542-197102000-00027. View

Lichtman M, Miller D, Cohen J, Waterhouse C . Reduced red cell glycolysis, 2, 3-diphosphoglycerate and adenosine triphosphate concentration, and increased hemoglobin-oxygen affinity caused by hypophosphatemia. Ann Intern Med. 1971; 74(4):562-8. DOI: 10.7326/0003-4819-74-4-562. View

Parfitt A . The spectrum of hypoparathyroidism. J Clin Endocrinol Metab. 1972; 34(1):152-8. DOI: 10.1210/jcem-34-1-152. View

10.

Lee D, Drinkard J, ROSEN V, Gonick H . The adult Fanconi syndrome: observations on etiology, morphology, renal function and mineral metabolism in three patients. Medicine (Baltimore). 1972; 51(2):107-38. View

11.

Silvis S, Paragas Jr P . Paresthesias, weakness, seizures, and hypophosphatemia in patients receiving hyperalimentation. Gastroenterology. 1972; 62(4):513-20. View

12.

BECK L, Goldberg M . Effects of acetazolamide and parathyroidectomy on renal transport of sodium, calcium, and phosphate. Am J Physiol. 1973; 224(5):1136-42. DOI: 10.1152/ajplegacy.1973.224.5.1136. View

13.

DAVID D, Sakai S, BRENNAN B, Riggio R, Cheigh J, STENZEL K . Hypercalcemia after renal transplantation. Long-term follow-up data. N Engl J Med. 1973; 289(8):398-401. DOI: 10.1056/NEJM197308232890804. View

14.

Bode J, Zelder O, Rumpelt H, Wittkamp U . Depletion of liver adenosine phosphates and metabolic effects of intravenous infusion of fructose or sorbitol in man and in the rat. Eur J Clin Invest. 1973; 3(5):436-41. DOI: 10.1111/j.1365-2362.1973.tb02211.x. View

15.

Abrams D, Silcott R, Terry R, Berne T, BARBOUR B . Antacid induction of phosphate depletion syndrome in renal failure. West J Med. 1974; 120(2):157-60. PMC: 1129366. View

16.

Craddock P, Yawata Y, VanSanten L, Gilberstadt S, Silvis S, JACOB H . Acquired phagocyte dysfunction. A complication of the hypophosphatemia of parenteral hyperalimentation. N Engl J Med. 1974; 290(25):1403-7. DOI: 10.1056/NEJM197406202902504. View

17.

de Vries H, BIJVOET O . Results of prolonged treatment of Paget's disease of bone with disodium ethane-1-hydroxy-1, 1-diphosphonate (EHDP). Neth J Med. 1974; 17(6):281-98. View

18.

Brereton H, Anderson T, Johnson R, Schein P . Hyperphosphatemia and hypocalcemia in Burkitt lymophoma. Complications of chemotherapy. Arch Intern Med. 1975; 135(2):307-9. View

19.

NUSYNOWITZ M, Frame B, KOLB F . The spectrum of the hypoparathyroid states: A classification based on physiologic principles. Medicine (Baltimore). 1976; 55(2):105-19. DOI: 10.1097/00005792-197603000-00001. View

20.

KOFFLER A, FRIEDLER R, Massry S . Acute renal failure due to nontraumatic rhabdomyolysis. Ann Intern Med. 1976; 85(1):23-8. DOI: 10.7326/0003-4819-85-1-23. View