Exceptional Survival Among Kentucky Stage IV Non-small Cell Lung Cancer Patients: Appalachian Versus Non-Appalachian Populations

Overview

Journal J Rural Health

Specialty Public Health

Date 2020 Nov 19

PMID 33210370

Citations 1

Authors

Vira Pravosud

Nathan L Vanderford

Bin Huang

Thomas C Tucker

Susanne M Arnold

Affiliations

Soon will be listed here.

Abstract

Purpose: To determine differences in exceptional survival (ES)-survival of 5 years or more past diagnosis-between stage IV non-small cell lung cancer (NSCLC) patients residing in the Appalachian versus non-Appalachian regions of Kentucky.

Methods: This was a population-based, retrospective case-control study of Kentucky patients, diagnosed with stage IV NSCLC between January 1, 2000, and December 31, 2011. The data were drawn from the Kentucky Cancer Registry.

Findings: Findings from the multivariable logistic regression revealed no significant differences in the odds of ES between patients who resided in Appalachian versus non-Appalachian Kentucky. Being female and undergoing surgery only as the first course of treatment were associated with higher odds of ES. Increasing age, unspecified histology, having poorly differentiated or undifferentiated carcinomas, and receiving radiation therapy only as the first course of treatment were associated with decreased odds of ES.

Conclusion: Differences in the odds of ES among stage IV NSCLC patients were not related to residence in Appalachian versus non-Appalachian Kentucky. ES was associated with other nongenetic and treatment factors that warrant further investigations.

Citing Articles

A new communication approach to encourage lung cancer screening action in rural eligible populations.

Boatman D, McCauley-Hixenbaugh L, Starkey A, Allen A, Kennedy-Rea S PEC Innov. 2024; 4:100298.

PMID: 38962501 PMC: 11219952. DOI: 10.1016/j.pecinn.2024.100298.

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