Stability of Engineered Micro or Nanobubbles for Biomedical Applications

Overview

Journal Pharmaceutics

Publisher MDPI

Date 2020 Nov 18

PMID 33202709

Citations 9

Authors

Beomjin Park

Semi Yoon

Yonghyun Choi

Jaehee Jang

Soomin Park

Jonghoon Choi

Affiliations

Soon will be listed here.

Abstract

A micro/nanobubble (MNB) refers to a bubble structure sized in a micrometer or nanometer scale, in which the core is separated from the external environment and is normally made of gas. Recently, it has been confirmed that MNBs can be widely used in angiography, drug delivery, and treatment. Thus, MNBs are attracting attention as they are capable of constructing a new contrast agent or drug delivery system. Additionally, in order to effectively use an MNB, the method of securing its stability is also being studied. This review highlights the factors affecting the stability of an MNB and the stability of the MNB within the ultrasonic field. It also discusses the relationship between the stability of the bubble and its applicability in vivo.

Citing Articles

Clinical Applications of Micro/Nanobubble Technology in Neurological Diseases.

Patel P, Latt S, Ravi K, Razavi M Biomimetics (Basel). 2024; 9(10).

PMID: 39451851 PMC: 11506587. DOI: 10.3390/biomimetics9100645.

Modifications of Nanobubble Therapy for Cancer Treatment.

Terlikowska K, Dobrzycka B, Terlikowski S Int J Mol Sci. 2024; 25(13).

PMID: 39000401 PMC: 11242568. DOI: 10.3390/ijms25137292.

Influence of protein nativity on the stability of bovine serum albumin coated microbubbles.

Dhara P, Shah N, Sundaram V, Srivastava A, Solovev A, Mei Y iScience. 2024; 27(3):109286.

PMID: 38482489 PMC: 10933459. DOI: 10.1016/j.isci.2024.109286.

Investigating the effects of ultrafine bubbles on bacterial growth.

Vu M, Le Hanh Tran N, Lam T, Tran A, Anh Le T, Nguyen K RSC Adv. 2024; 14(3):2159-2169.

PMID: 38205233 PMC: 10777100. DOI: 10.1039/d3ra07454d.

NanoBubble-Mediated Oxygenation: Elucidating the Underlying Molecular Mechanisms in Hypoxia and Mitochondrial-Related Pathologies.

Viafara Garcia S, Khan M, Haidar Z, Acevedo Cox J Nanomaterials (Basel). 2023; 13(23).

PMID: 38063756 PMC: 10708518. DOI: 10.3390/nano13233060.

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