Amnesia in a Patient with Rheumatoid Arthritis: A Case of Granulomatosis with Polyangiitis

Overview

Journal Case Rep Rheumatol

Publisher Wiley

Date 2020 Nov 12

PMID 33178476

Authors

Pablo Weilg

Giancarlo Diaz-Zamora

Larry Young

Affiliations

Soon will be listed here.

Abstract

A 56-year-old male with a history of seropositive rheumatoid arthritis complained of polyarthritis and forgetfulness. The initial CT scan of the head without contrast was negative for acute pathologies. However, as he continued to decline despite being on oral prednisone, an MRI of the head was ordered and revealed a subtle small region of acute infarction in the left mammillary body. He was diagnosed with granulomatosis with polyangiitis in light of his positive C-ANCA antibodies, PR3 antibody, and a kidney biopsy, which showed focal necrotizing pauci-immune crescentic glomerulonephritis. Despite undergoing steroid pulse therapy, the patient developed diffuse alveolar damage which finally responded to rituximab infusion.

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