Variant Analysis of 1,040 SARS-CoV-2 Genomes

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2020 Nov 5

PMID 33152019

Citations 21

Authors

Eric C Rouchka

Julia H Chariker

Donghoon Chung

Affiliations

Soon will be listed here.

Abstract

The severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral genome is an RNA virus consisting of approximately 30,000 bases. As part of testing efforts, whole genome sequencing of human isolates has resulted in over 1,600 complete genomes publicly available from GenBank. We have performed a comparative analysis of the sequences, in order to detect common mutations within the population. Analysis of variants occurring within the assembled genomes yields 417 variants occurring in at least 1% of the completed genomes, including 229 within the 5' untranslated region (UTR), 152 within the 3'UTR, 2 within intergenic regions and 34 within coding sequences.

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