A Case of Adult-Onset Still's Disease with Positive Antinuclear Antibodies

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2020 Nov 5

PMID 33150111

Citations 3

Authors

Harini Lakshman

Pal Satyajit Singh Athwal

Anitha Gondi

Sandaljit Dhillon

Basim A Towfiq

Affiliations

Soon will be listed here.

Abstract

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder involving multiple systems. It can present a wide range of symptoms like maculopapular rash, fever, and arthralgia, which may overlap with many other disorders, making it difficult to diagnose. Unknown etiology and no diagnostic tests further make it complex to establish the diagnosis of AOSD. We report the case of a 30-year-old female who presented with persistent rash, joint pain, and fever, along with positive antinuclear antibodies (ANA), diagnosed with this condition. The patient improved with corticosteroids and the plan is to start disease-modifying antirheumatic drugs (DMARDs) after tapering off steroids.

Citing Articles

A Case of Adult-Onset Still's Disease With Positive Antinuclear Antibodies and Positive Antineutrophil Cytoplasmic Antibodies.

Vasilev V, Savvina M, Argunova A, Danilova A Cureus. 2024; 16(5):e61399.

PMID: 38953085 PMC: 11215933. DOI: 10.7759/cureus.61399.

Chronic Adult-Onset Still's Disease With Positive Antinuclear Antibodies: Navigating Diagnostic Dilemmas and Clinical Implications.

Nagpure K, Raju P, Dube A, Verma I, Kumbhalkar S Cureus. 2024; 16(3):e56776.

PMID: 38650770 PMC: 11034574. DOI: 10.7759/cureus.56776.

Case Report: A Rare Case of Elderly-Onset Adult-Onset Still's Disease in a Patient With Systemic Lupus Erythematosus.

Hirooka Y, Okuda S, Sugiyama M, Shiga T, Nozaki Y, Kinoshita K Front Immunol. 2022; 13:822169.

PMID: 35116046 PMC: 8803898. DOI: 10.3389/fimmu.2022.822169.

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