Beauvericin and Enniatins: In Vitro Intestinal Effects

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2020 Nov 3

PMID 33138307

Citations 23

Authors

Alessia Bertero

Paola Fossati

Doriana Eurosia Angela Tedesco

Francesca Caloni

Affiliations

Soon will be listed here.

Abstract

Food and feed contamination by emerging mycotoxins beauvericin and enniatins is a worldwide health problem and a matter of great concern nowadays, and data on their toxicological behavior are still scarce. As ingestion is the major route of exposure to mycotoxins in food and feed, the gastrointestinal tract represents the first barrier encountered by these natural contaminants and the first structure that could be affected by their potential detrimental effects. In order to perform a complete and reliable toxicological evaluation, this fundamental site cannot be disregarded. Several in vitro intestinal models able to recreate the different traits of the intestinal environment have been applied to investigate the various aspects related to the intestinal toxicity of emerging mycotoxins. This review aims to depict an overall and comprehensive representation of the in vitro intestinal effects of beauvericin and enniatins in humans from a species-specific perspective. Moreover, information on the occurrence in food and feed and notions on the regulatory aspects will be provided.

Citing Articles

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First Total Syntheses of Beauvericin A and -Beauvericin A.

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