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Interaction Between Stress Hormones and Phagocytic Cells and Its Effect on the Health Status of Dairy Cows: A Review

Overview
Journal Vet World
Date 2020 Nov 2
PMID 33132594
Citations 7
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Abstract

Dairy cows are exposed to various stressors during their production cycle that makes them more susceptible to various diseases. Phagocytes (neutrophils and macrophages) are important soldiers of the innate immune system. Neutrophils are the first responders to an inflammatory response and stress and kill pathogens by generating reactive oxygen species and by the release of various antimicrobial peptides, enzymes, neutrophil extracellular trap formation, etc. Macrophages, the other phagocytes, are also the cleanup crew for the innate immune system that removes debris, pathogens, and dead neutrophils later on after an inflammatory response. The neuroendocrine system along with phagocytes exhibits an immunomodulatory potential during stressful conditions. Neuroendocrine system directly affects the activity of phagocytes by communicating bidirectionally through shared receptors and messenger molecules such as hormones, neurotransmitters, or cytokines. Different immune cells may show variable responses to each hormone. Short time exposure to stress can be beneficial, but repeated or extended exposure to stress may be detrimental to the overall health and well-being of an animal. Although some stresses associated with farming practices in dairy cows are unavoidable, better understanding of the interactions occurring between various stress hormones and phagocytic cells can help to reduce stress, improve productivity and animal welfare. This review highlights the role played by various stress hormones in modulating phagocytic cell performance of dairy cattle under inflammatory conditions.

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References
1.
Bhat S, Ahmad S, Ibeagha-Awemu E, Mobashir M, Dar M, Mumtaz P . Comparative milk proteome analysis of Kashmiri and Jersey cattle identifies differential expression of key proteins involved in immune system regulation and milk quality. BMC Genomics. 2020; 21(1):161. PMC: 7023774. DOI: 10.1186/s12864-020-6574-4. View

2.
Pathak R, Prasad S, Kumaresan A, Kaur M, Manimaran A, Dang A . Alterations in cortisol concentrations and expression of certain genes associated with neutrophil functions in cows developing retention of fetal membranes. Vet Immunol Immunopathol. 2015; 168(3-4):164-8. DOI: 10.1016/j.vetimm.2015.09.003. View

3.
Bhatia A, Sekhon H, Kaur G . Sex hormones and immune dimorphism. ScientificWorldJournal. 2014; 2014:159150. PMC: 4251360. DOI: 10.1155/2014/159150. View

4.
Sapolsky R, Romero L, Munck A . How do glucocorticoids influence stress responses? Integrating permissive, suppressive, stimulatory, and preparative actions. Endocr Rev. 2000; 21(1):55-89. DOI: 10.1210/edrv.21.1.0389. View

5.
Alhussien M, Manjari P, Mohammed S, Sheikh A, Reddi S, Dixit S . Incidence of mastitis and activity of milk neutrophils in Tharparkar cows reared under semi-arid conditions. Trop Anim Health Prod. 2016; 48(6):1291-5. DOI: 10.1007/s11250-016-1068-8. View