Metal Nanoparticle Alters Adenine Induced Charge Transfer Kinetics of Vitamin K3 in Magnetic Field

Overview

Journal Sci Rep

Specialty Science

Date 2020 Oct 29

PMID 33116189

Authors

Ranjan Kumar Behera

Abhishek Sau

Leepsa Mishra

Sankalan Mondal

Kallol Bera

Satish Kumar

Samita Basu

Manas Kumar Sarangi

Affiliations

Soon will be listed here.

Abstract

In this article, we highlight the alterations in the photoinduced electron transfer (ET) and hydrogen atom transfer (HAT) pathways between an anti-tumor drug vitamin-K3 (MQ) and a nucleobase adenine (ADN) in the presence of gold (Au) and iron (Fe) nanoparticles (NPs). Inside the confined micellar media, with laser flash photolysis corroborated with an external magnetic field (MF), we have detected the transient geminate radicals of MQ and ADN, photo-generated through ET and HAT. We observe that the presence of AuNP on the MQ-ADN complex (MQ-ADN) assists HAT by limiting the ET channel, on the other hand, FeNP on the MQ-ADN complex (MQ-ADN) mostly favors a facile PET. We hypothesize that through selective interactions of the ADN molecules with AuNP and MQ molecules with FeNP, a preferential HAT and PET process is eased. The enhanced HAT and PET have been confirmed by the escape yields of radical intermediates by time-resolved transient absorption spectroscopy in the presence of MF.

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