Biosynthesis and Biological Activities of Newly Discovered Amaryllidaceae Alkaloids

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2020 Oct 29

PMID 33113950

Citations 12

Authors

Seydou Ka

Manoj Koirala

Natacha Merindol

Isabel Desgagne-Penix

Affiliations

Soon will be listed here.

Abstract

Alkaloids are an important group of specialized nitrogen metabolites with a wide range of biochemical and pharmacological effects. Since the first publication on lycorine in 1877, more than 650 alkaloids have been extracted from Amaryllidaceae bulbous plants and clustered together as the Amaryllidaceae alkaloids (AAs) family. AAs are specifically remarkable for their diverse pharmaceutical properties, as exemplified by the success of galantamine used to treat the symptoms of Alzheimer's disease. This review addresses the isolation, biological, and structure activity of AAs discovered from January 2015 to August 2020, supporting their therapeutic interest.

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