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Cerebral Angiography with Non-ionic (metrizamide) and Ionic (meglumine Metrizoate) Watersoluble Contrast Media. A Comparative Study with Double Blind Technic

Overview
Journal Neuroradiology
Specialties Neurology
Radiology
Date 1977 Aug 25
PMID 331137
Citations 15
Authors
I O SKALPE
A Lundervold
K Tjorstad
Affiliations
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Abstract

The adverse effects of cerebral angiography with metrizamide and meglumine metrizoate were compared in 20 patients for each contrast medium using a double blind technic. Deterioration of the EEG and bradycardial reactions were seen more often with meglumine metrizoate than with metrizamide and these differences were statistically significant. Metrizamide also had a shorter circulation time, less influence on the blood pressure and EMG than meglumine metrizoate, but these differences were not statistically significant. The clinical examinations showed no difference in the minor adverse effects. One patient had transient hemiparesis and dysarthria after angiography with meglumine metrizoate but no serious complications were seen in the others.

Citing Articles

Intra-arterial digital subtraction angiography with isotonic dimeric (iodixanol) and monomeric (iohexol) nonionic contrast media: radiographic, clinical and neurophysiological evaluation.

Hekster R, Morre H, Cleyndert P, Zapletal J, Sinnige L, Bolstad B Neuroradiology. 1995; 37(1):48-50.

PMID: 7708189 DOI: 10.1007/BF00588519.

The toxicity of the non-ionic water-soluble contrast media iohexol and metrizamide (Amipaque) in selective vertebral angiography. An experimental study in rabbits.

SKALPE I Neuroradiology. 1981; 20(5):235-9.

PMID: 7465042 DOI: 10.1007/BF00342090.

Complications of cerebral angiography. Comparing metrizamide (Amipaque) and meglumine metrizoate (Isopaque Cerebral).

SKALPE I, Lundervold A, Tjorstad K Neuroradiology. 1980; 19(2):67-71.

PMID: 7366836 DOI: 10.1007/BF00342597.

Cerebral angiography with the non-ionic water-soluble contrast medium iohexol and meglumine-Ca-metrizoate. A randomized double blind parallel study in man.

Nakstad P, Sortland O, Aaserud O, Lundervold A Neuroradiology. 1982; 23(4):199-202.

PMID: 7121809 DOI: 10.1007/BF00342540.

Iohexol compared to meglumine-Ca-metrizoate in common carotid angiography. A randomized double blind cross-over study in man.

Nakstad P, Sortland O, Aaserud O Neuroradiology. 1983; 25(1):33-6.

PMID: 6856079 DOI: 10.1007/BF00327477.

References
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