» Articles » PMID: 33107003

Factors Influencing Implementation of a Colorectal Cancer Screening Improvement Program in Community Health Centers: an Applied Use of Configurational Comparative Methods

Overview
Publisher Springer
Specialty General Medicine
Date 2020 Oct 27
PMID 33107003
Citations 32
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Evidence-based programs such as mailed fecal immunochemical test (FIT) outreach can only affect health outcomes if they can be successfully implemented. However, attempts to implement programs are often limited by organizational-level factors.

Objectives: As part of the Strategies and Opportunities to Stop Colon Cancer in Priority Populations (STOP CRC) pragmatic trial, we evaluated how organizational factors impacted the extent to which health centers implemented a mailed FIT outreach program.

Design: Eight health centers participated in STOP CRC. The intervention consisted of customized electronic health record tools and clinical staff training to facilitate mailing of an introduction letter, FIT kit, and reminder letter. Health centers had flexibility in how they delivered the program.

Main Measures: We categorized the health centers' level of implementation based on the proportion of eligible patients who were mailed a FIT kit, and applied configurational comparative methods to identify combinations of relevant organizational-level and program-level factors that distinguished among high, medium, and low implementing health centers. The factors were categorized according to the Consolidated Framework for Implementation Research model.

Key Results: FIT tests were mailed to 21.0-81.7% of eligible participants at each health center. We identified a two-factor solution that distinguished among levels of implementation with 100% consistency and 100% coverage. The factors were having a centralized implementation team (inner setting) and mailing the introduction letter in advance of the FIT kit (intervention characteristics). Health centers with high levels of implementation had the joint presence of both factors. In health centers with medium levels of implementation, only one factor was present. Health centers with low levels of implementation had neither factor present.

Conclusions: Full implementation of the STOP CRC intervention relied on a centralized implementation team with dedicated staffing time, and the advance mailing of an introduction letter.

Trial Registration: ClinicalTrials.gov Identifier: NCT01742065 Registered 05 December 2012-Prospectively registered.

Citing Articles

Organizational readiness for implementation: a qualitative assessment to explain survey responses.

McClam M, Workman L, Walker T, Dias E, Craig D, Padilla J BMC Health Serv Res. 2025; 25(1):36.

PMID: 39773649 PMC: 11705772. DOI: 10.1186/s12913-024-12149-8.


Barriers and proposed solutions to at-home colorectal cancer screening tests in medically underserved health centers across three US regions to inform a randomized trial.

Brodney S, Bhat R, Tuan J, Johnson G, May F, Glenn B Cancer Med. 2024; 13(15):e70040.

PMID: 39118261 PMC: 11310093. DOI: 10.1002/cam4.70040.


Reducing sickness absence among public-sector healthcare employees: the difference-making roles of managerial and employee participation.

Akerstrom M, Severin J, Miech E, Wikstrom E, Roczniewska M Int Arch Occup Environ Health. 2024; 97(3):341-351.

PMID: 38409534 PMC: 10944807. DOI: 10.1007/s00420-024-02048-0.


Factors Affecting Post-trial Sustainment or De-implementation of Study Interventions: A Narrative Review.

Green T, Bosworth H, Coronado G, DeBar L, Green B, Huang S J Gen Intern Med. 2024; 39(6):1029-1036.

PMID: 38216853 PMC: 11074060. DOI: 10.1007/s11606-023-08593-7.


Methods for scaling up an outreach intervention to increase colorectal cancer screening rates in rural areas.

Coury J, Coronado G, Currier J, Kenzie E, Petrik A, Badicke B Implement Sci Commun. 2024; 5(1):6.

PMID: 38191536 PMC: 10775579. DOI: 10.1186/s43058-023-00540-1.


References
1.
Levin T, Corley D, Jensen C, Schottinger J, Quinn V, Zauber A . Effects of Organized Colorectal Cancer Screening on Cancer Incidence and Mortality in a Large Community-Based Population. Gastroenterology. 2018; 155(5):1383-1391.e5. PMC: 6240353. DOI: 10.1053/j.gastro.2018.07.017. View

2.
Green B, Anderson M, Cook A, Chubak J, Fuller S, Meenan R . A centralized mailed program with stepped increases of support increases time in compliance with colorectal cancer screening guidelines over 5 years: A randomized trial. Cancer. 2017; 123(22):4472-4480. PMC: 5673524. DOI: 10.1002/cncr.30908. View

3.
Cole A, Esplin A, Baldwin L . Adaptation of an Evidence-Based Colorectal Cancer Screening Program Using the Consolidated Framework for Implementation Research. Prev Chronic Dis. 2015; 12:E213. PMC: 4674444. DOI: 10.5888/pcd12.150300. View

4.
Brenner A, Getrich C, Pignone M, Rhyne R, Hoffman R, McWilliams A . Comparing the effect of a decision aid plus patient navigation with usual care on colorectal cancer screening completion in vulnerable populations: study protocol for a randomized controlled trial. Trials. 2014; 15:275. PMC: 4100055. DOI: 10.1186/1745-6215-15-275. View

5.
Cragun D, Pal T, Vadaparampil S, Baldwin J, Hampel H, DeBate R . Qualitative Comparative Analysis: A Hybrid Method for Identifying Factors Associated with Program Effectiveness. J Mix Methods Res. 2016; 10(3):251-272. PMC: 4941817. DOI: 10.1177/1558689815572023. View