High-intensity Interval Training in the Prehabilitation of Cancer Patients-a Systematic Review and Meta-analysis

Overview

Journal Support Care Cancer

Specialties Critical Care
Oncology

Date 2020 Oct 27

PMID 33106975

Citations 28

Authors

Stefano Palma

Timothy Hasenoehrl

Galateja Jordakieva

Dariga Ramazanova

Richard Crevenna

Affiliations

Soon will be listed here.

Abstract

Purpose: To evaluate the impact of high-intensity interval training (HIIT) on health-related outcome parameters in the prehabilitation of patients diagnosed with cancer.

Methods: A systematic review and meta-analysis of comparative studies on HIIT in cancer prehabilitation conducted by screening standard databases from their inception to March 30, 2020. Outcomes of interest included cardiorespiratory fitness, feasibility, safety, clinical, and patient-reported outcomes.

Results: Of the 855 identified studies, 8 articles met the inclusion criteria (7 randomized, 1 non-randomized controlled trial) with a total of 896 patients. The study protocols were heterogeneous, but the methodological quality ranged from good to high according to PEDro scale. Meta-analysis revealed a significant improvement of peak oxygen consumption (VOpeak) achieved with HIIT compared to usual care. Furthermore, HIIT was feasible and safe, showing low risk of adverse events and positive effects on health-related outcomes in prehabilitative settings.

Conclusion: In the phase of prehabilitation, HIIT has potential health benefits in patients diagnosed with cancer and is feasible and safe to perform. Nonetheless, larger randomized controlled trials focusing on long-term effects (such as cancer recurrence or survival rates) are missing, to underline the potential relevance of HIIT for cancer patients.

Citing Articles

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