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Electroacupuncture Versus Analgesics for Patients with Stage IIIB Cervical Cancer Post Cisplatin Chemotherapy

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Journal Med Acupunct
Date 2020 Oct 26
PMID 33101574
Citations 1
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Abstract

The prevalence of pain at advanced cervical cancer stages is increasing. Existing World Health Organization recommendations for management comprises a 3-step ladder of analgesic therapy but this still cannot address this pain optimally. An alternative therapy used to reduce pain, acupuncture, is almost without side-effects, is safe, and is easy to implement. This study compared electroacupuncture (EA) versus paracetamol 500 mg +10-mg codeine therapy for patients with stage-IIIB cervical cancer post cisplatin chemotherapy. Participants were divided into 2 groups (treatment and control groups). A quasiexperimental study was conducted using a nonequivalent control group pretest-post-test design. Participants in the treatment group were given EA for 30 minutes 10 times over 3 weeks, while participants in the control group were given paracetamol 3 × 500 mg and codeine 3 × 10 mg orally every day for 3 weeks. Statistical analysis used paired -tests, a Wilcoxon test, an independent -test, or a Mann-Whitney- test with  < 0.05. Pretest and post-test pain-scale levels were 5.39 ± 0.62 and 4.57 ± 0.88, respectively ( < 0.001). Average endorphin-β levels at pretest and post-test were 571.80 ± 281.13 and 491.14 ± 272.14, respectively ( = 0.818). Median values of quality of life at pretest and post-test were 681.75 (range: 503.80-915.20) and 635.25 (range: 538.20-781.20;  = 0.383), respectively. Pain-control therapy using drugs or EA produces similar results. However, EA, subjectively, produces improved pain-scale results better than pharmaceuticals.

Citing Articles

How does pretreatment expectancy influence pain outcomes with electroacupuncture and battlefield acupuncture in cancer survivors?: Pretreatment expectancy and pain reduction by acupuncture.

Li X, Baser R, Bryl K, Amann L, Chimonas S, Mao J Integr Med Res. 2024; 13(2):101040.

PMID: 38721341 PMC: 11077026. DOI: 10.1016/j.imr.2024.101040.

References
1.
Portenoy R, Kornblith A, Wong G, Vlamis V, Lepore J, Loseth D . Pain in ovarian cancer patients. Prevalence, characteristics, and associated symptoms. Cancer. 1994; 74(3):907-15. DOI: 10.1002/1097-0142(19940801)74:3<907::aid-cncr2820740318>3.0.co;2-#. View

2.
Kawakita K, Okada K . Acupuncture therapy: mechanism of action, efficacy, and safety: a potential intervention for psychogenic disorders?. Biopsychosoc Med. 2014; 8(1):4. PMC: 3996195. DOI: 10.1186/1751-0759-8-4. View

3.
Perwitasari D, Atthobari J, Dwiprahasto I, Hakimi M, Gelderblom H, Putter H . Translation and validation of EORTC QLQ-C30 into Indonesian version for cancer patients in Indonesia. Jpn J Clin Oncol. 2011; 41(4):519-29. DOI: 10.1093/jjco/hyq243. View

4.
Paley C, Johnson M, Tashani O, Bagnall A . Acupuncture for cancer pain in adults. Cochrane Database Syst Rev. 2015; (10):CD007753. PMC: 6513493. DOI: 10.1002/14651858.CD007753.pub3. View

5.
Weiss S, Emanuel L, Fairclough D, Emanuel E . Understanding the experience of pain in terminally ill patients. Lancet. 2001; 357(9265):1311-5. DOI: 10.1016/S0140-6736(00)04515-3. View