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Guillain-Barré Syndrome After Varicella-zoster Infection. Report of Two Cases

Overview
Journal J Neurol
Specialty Neurology
Date 1987 Aug 1
PMID 3309194
Citations 10
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Abstract

Two patients developed Guillain-Barré syndrome after varicella-zoster infection; a 4-year-old boy after chickenpox and a 74-year-old man after shingles. Both had decreased CD8-positive lymphocytes in the blood during the course of their illness. These cases and others reported in the literature suggest that varicella-zoster infection is a significant but rare trigger factor of Guillain-Barré syndrome. An alteration in the balance of helper and suppressor lymphocytes may be an important pathogenetic mechanism.

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