The Osmotically Regulated ProU Locus of Salmonella Typhimurium Encodes a Periplasmic Betaine-binding Protein

Overview

Journal J Gen Microbiol

Specialty Microbiology

Date 1987 Feb 1

PMID 3309148

Citations 17

Authors

C F Higgins

L Sutherland

J Cairney

I R Booth

Affiliations

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Abstract

The proU locus of Salmonella typhimurium encodes an osmotically induced betaine transport system. We have identified a 31 kDa periplasmic protein, encoded by proU, whose synthesis is induced by osmotic stress. A specific betaine-binding activity with a KD of about 1 microM is also present in the periplasm of osmotically induced cells. This activity is absent in those proU mutants which lack the 31 kDa periplasmic protein. Thus, ProU is a periplasmic binding-protein-dependent transport system.

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