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Protein-Stabilized Palm-Oil-in-Water Emulsification Using Microchannel Array Devices Under Controlled Temperature

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2020 Oct 22
PMID 33086710
Citations 1
Authors
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Abstract

Microchannel (MC) emulsification for the preparation of monodisperse oil-in-water (O/W) and water-in-oil-in-water (W/O/W) emulsions containing palm oil as the oil phase was investigated for application as basic material solid/semi-solid lipid microspheres for delivery carriers of nutrients and drugs. Emulsification was characterized by direct observation of droplet generation under various operation conditions, as such, the effects of type and concentration of emulsifiers, emulsification temperature, MC structure, and flow rate of to-be-dispersed phase on droplet generation via MC were investigated. Sodium caseinate (SC) was confirmed as the most suitable emulsifier among the examined emulsifiers, and monodisperse O/W and W/O/W emulsions stabilized by it were successfully obtained with 20 to 40 µm mean diameter () using different types of MCs.

Citing Articles

Enhancing the Formation and Stability of Oil-In-Water Emulsions Prepared by Microchannels Using Mixed Protein Emulsifiers.

Jiao Y, Zhao Y, Chang Y, Ma Z, Kobayashi I, Nakajima M Front Nutr. 2022; 9:822053.

PMID: 35711552 PMC: 9196885. DOI: 10.3389/fnut.2022.822053.

References
1.
Edem D . Palm oil: biochemical, physiological, nutritional, hematological, and toxicological aspects: a review. Plant Foods Hum Nutr. 2003; 57(3-4):319-41. DOI: 10.1023/a:1021828132707. View

2.
Zhang Y, Shen L, Wang T, Li H, Huang R, Zhang Z . Taste masking of water-soluble drug by solid lipid microspheres: a child-friendly system established by reversed lipid-based nanoparticle technique. J Pharm Pharmacol. 2020; 72(6):776-786. DOI: 10.1111/jphp.13245. View

3.
Muller R, Mader K, Gohla S . Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur J Pharm Biopharm. 2000; 50(1):161-77. DOI: 10.1016/s0939-6411(00)00087-4. View

4.
McClements D . Crystals and crystallization in oil-in-water emulsions: implications for emulsion-based delivery systems. Adv Colloid Interface Sci. 2012; 174:1-30. DOI: 10.1016/j.cis.2012.03.002. View

5.
Sugiura S, Nakajima M, Yamamoto K, Iwamoto S, Oda T, Satake M . Preparation characteristics of water-in-oil-in-water multiple emulsions using microchannel emulsification. J Colloid Interface Sci. 2003; 270(1):221-8. DOI: 10.1016/j.jcis.2003.08.021. View