The Tomato Receptor CuRe1 Senses a Cell Wall Protein to Identify Cuscuta As a Pathogen

Overview

Journal Nat Commun

Specialty Biology

Date 2020 Oct 21

PMID 33082345

Citations 25

Authors

Volker Hegenauer

Peter Slaby

Max Korner

Julien-Alexander Bruckmuller

Ronja Burggraf

Isabell Albert

Bettina Kaiser

Birgit Loffelhardt

Irina Droste-Borel

Jan Sklenar

Frank L H Menke

Boris Macek

Aashish Ranjan

Neelima Sinha

Thorsten Nurnberger

Georg Felix

Kirsten Krause

Mark Stahl

Markus Albert

Affiliations

Soon will be listed here.

Abstract

Parasitic plants of the genus Cuscuta penetrate shoots of host plants with haustoria and build a connection to the host vasculature to exhaust water, solutes and carbohydrates. Such infections usually stay unrecognized by the host and lead to harmful host plant damage. Here, we show a molecular mechanism of how plants can sense parasitic Cuscuta. We isolated an 11 kDa protein of the parasite cell wall and identified it as a glycine-rich protein (GRP). This GRP, as well as its minimal peptide epitope Crip21, serve as a pathogen-associated molecular pattern and specifically bind and activate a membrane-bound immune receptor of tomato, the Cuscuta Receptor 1 (CuRe1), leading to defense responses in resistant hosts. These findings provide the initial steps to understand the resistance mechanisms against parasitic plants and further offer great potential for protecting crops by engineering resistance against parasitic plants.

Citing Articles

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