An Outbreak of a Respiratory Disorder at a Russian Swine Farm Associated with the Co-Circulation of and

Overview

Journal Viruses

Publisher MDPI

Specialty Microbiology

Date 2020 Oct 20

PMID 33076391

Citations 3

Authors

Sergei Raev

Anton Yuzhakov

Alexandr Bulgakov

Ludmila Kostina

Alexei Gerasianinov

Oleg Verkhovsky

Alexei Zaberezhny

Taras Aliper

Affiliations

Soon will be listed here.

Abstract

We conducted a cross-sectional study to identify the major respiratory pathogen responsible for an outbreak of respiratory disease at a swine farm in West Siberia in 2019. We discovered that the peak of morbidity and mortality coincided with a high level of porcine reproductive and respiratory syndrome virus () 1 and 2-related viremia. Based on longer PRRSV2 viremia, the dominant role of PRRSV2 over PRRSV1 in the outbreak was assumed. Phylogenetic analysis revealed that the PRRSV1 strain belonged to sub-genotype 2-one of the predominant groups of genotype 1 PRRSVs in Russia. A partial open reading frame 7 sequence of the PRRSV2 isolate demonstrated a high identity with modified live vaccine-related strains from Denmark (93%) and wild-type VR2332 (92%). We identified the first instance of mixed infection in Russia. This finding indicates that further field investigations are needed to access epidemiology in eastern Europe.

Citing Articles

Prevalence and genetic evolution of porcine reproductive and respiratory syndrome virus in commercial fattening pig farms in China.

Li C, Zhao J, Li W, Xu H, Gong B, Sun Q Porcine Health Manag. 2024; 10(1):5.

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Metagenomic Approach Reveals the Second Subtype of PRRSV-1 in a Pathogen Spectrum during a Clinical Outbreak with High Mortality in Western Siberia, Russia.

Krasnikov N, Yuzhakov A, Aliper T, Gulyukin A Viruses. 2023; 15(2).

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A Molecular and Epidemiological Description of a Severe Porcine Reproductive and Respiratory Syndrome Outbreak in a Commercial Swine Production System in Russia.

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PMID: 35215966 PMC: 8875681. DOI: 10.3390/v14020375.

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