» Articles » PMID: 33072699

Geographical Distribution of Genetic Variants and Lineages of SARS-CoV-2 in Chile

Overview
Specialty Public Health
Date 2020 Oct 19
PMID 33072699
Citations 19
Authors
Affiliations
Soon will be listed here.
Abstract

The pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a worldwide public health concern. First confined in China and then disseminated widely across Europe and America, SARS-CoV-2 has impacted and moved the scientific community around the world to working in a fast and coordinated way to collect all possible information about this virus and generate new strategies and protocols to try to stop the infection. During March 2020, more than 16,000 full viral genomes have been shared in public databases that allow the construction of genetic landscapes for tracking and monitoring the viral advances over time and study the genomic variations present in geographic regions. In this work, we present the occurrence of genetic variants and lineages of SARS-CoV-2 in Chile during March to April 2020. Complete genome analysis of 141 viral samples from different regions of Chile revealed a predominance of variant D614G like in Europe and the USA and the major presence of lineage B.1. These findings could help take control measures due to the similarity of the viral variants present in Chile, compared with other countries, and monitor the dynamic change of virus variants in the country.

Citing Articles

Routes of importation and spatial dynamics of SARS-CoV-2 variants during localized interventions in Chile.

Gutierrez B, Tsui J, Pullano G, Mazzoli M, Gangavarapu K, Inward R PNAS Nexus. 2024; 3(11):pgae483.

PMID: 39525554 PMC: 11547135. DOI: 10.1093/pnasnexus/pgae483.


SARS-CoV-2 infectivity and antigenic evasion: spotlight on isolated Omicron sub-lineages.

Barrera A, Martinez-Valdebenito C, Angulo J, Palma C, Hormazabal J, Vial C Front Med (Lausanne). 2024; 11:1414331.

PMID: 39267969 PMC: 11390582. DOI: 10.3389/fmed.2024.1414331.


Early mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants in Chile.

Orostica K, Mohr S, Dehning J, Bauer S, Medina-Ortiz D, Iftekhar E Sci Rep. 2024; 14(1):16000.

PMID: 38987406 PMC: 11237036. DOI: 10.1038/s41598-024-66885-2.


SARS-CoV-2 outbreak: role of viral proteins and genomic diversity in virus infection and COVID-19 progression.

Hussein H, Thabet A, Wardany A, El-Adly A, Ali M, Hassan M Virol J. 2024; 21(1):75.

PMID: 38539202 PMC: 10967059. DOI: 10.1186/s12985-024-02342-w.


Modelling quarantine effects on SARS-CoV-2 epidemiological dynamics in Chilean communes and their relationship with the Social Priority Index.

Salinas D, Bustamante M, Gallardo M PeerJ. 2023; 11:e14892.

PMID: 36923504 PMC: 10010178. DOI: 10.7717/peerj.14892.


References
1.
Ciotti M, Angeletti S, Minieri M, Giovannetti M, Benvenuto D, Pascarella S . COVID-19 Outbreak: An Overview. Chemotherapy. 2020; 64(5-6):215-223. PMC: 7179549. DOI: 10.1159/000507423. View

2.
Korber B, Fischer W, Gnanakaran S, Yoon H, Theiler J, Abfalterer W . Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus. Cell. 2020; 182(4):812-827.e19. PMC: 7332439. DOI: 10.1016/j.cell.2020.06.043. View

3.
Castillo A, Parra B, Tapia P, Acevedo A, Lagos J, Andrade W . Phylogenetic analysis of the first four SARS-CoV-2 cases in Chile. J Med Virol. 2020; 92(9):1562-1566. PMC: 7228331. DOI: 10.1002/jmv.25797. View

4.
Deng X, Gu W, Federman S, du Plessis L, Pybus O, Faria N . Genomic surveillance reveals multiple introductions of SARS-CoV-2 into Northern California. Science. 2020; 369(6503):582-587. PMC: 7286545. DOI: 10.1126/science.abb9263. View

5.
Moorthy V, Restrepo A, Preziosi M, Swaminathan S . Data sharing for novel coronavirus (COVID-19). Bull World Health Organ. 2020; 98(3):150. PMC: 7047033. DOI: 10.2471/BLT.20.251561. View